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[二丙基乙酰胺正常胸腺效应的临床研究]

[Clinical study of the normothymic effect of dipropylacetamide].

作者信息

Semadeni G W

出版信息

Acta Psychiatr Belg. 1976 May;76(3):458-66.

PMID:798467
Abstract

On the basis of his results, obtained during a long term study of 32 patients presenting cyclic variations of mood with a known frequency, the author concludes that dipropylacetamide permits to stabilise mood in about 70% of all cases through a supression of relapses or by reducing significantly their frequency. No biological changes were observed and the clinical tolerance of the drug was excellent in most cases. This drug constitutes a variable alternative to lithium treatment, and lacks the well known lithium side effects and limitations.

摘要

基于对32例已知频率呈现情绪周期性变化患者的长期研究结果,作者得出结论:二丙基乙酰胺可通过抑制复发或显著降低复发频率,使约70%的患者情绪稳定。未观察到生物学变化,且该药物在大多数情况下临床耐受性良好。这种药物是锂盐治疗的一种可变替代方案,且没有锂盐众所周知的副作用和局限性。

相似文献

1
[Clinical study of the normothymic effect of dipropylacetamide].[二丙基乙酰胺正常胸腺效应的临床研究]
Acta Psychiatr Belg. 1976 May;76(3):458-66.
2
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Minerva Med. 1977 Jul 7;68(33):2309-14.
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[Use of valpromide in psychiatric therapeutics].[丙戊酰胺在精神科治疗中的应用]
Encephale. 1987 Nov-Dec;13(6):367-73.
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[Acupuncture, "vital" drugs and psychotropic agents in psychiatric patients. 50 cases].[针刺疗法、“重要”药物及精神药物用于精神病患者。50例]
Minerva Med. 1978 Sep 22;69(44):3003-9.
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[Sodium di-n-propylacetate: evaluation of its so-called psychotropic effect. A controlled study].
Ugeskr Laeger. 1977 May 2;139(18):1069-73.
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Rational polypharmacy in the bipolar affective disorders.双相情感障碍中的合理联合用药
Epilepsy Res Suppl. 1996;11:153-80.
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[Sodium di-n-propylacetate, effect in the treatment of resistant epilepsy. A controlled study].
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引用本文的文献

1
Diagnosis and Treatment of Cyclothymia: The "Primacy" of Temperament.环性心境障碍的诊断与治疗:气质的“首要性”
Curr Neuropharmacol. 2017 Apr;15(3):372-379. doi: 10.2174/1570159X14666160616120157.
2
Clinical pharmacology of valpromide.
Clin Pharmacokinet. 1991 Feb;20(2):114-22. doi: 10.2165/00003088-199120020-00003.