Semadeni G W
Acta Psychiatr Belg. 1976 May;76(3):458-66.
On the basis of his results, obtained during a long term study of 32 patients presenting cyclic variations of mood with a known frequency, the author concludes that dipropylacetamide permits to stabilise mood in about 70% of all cases through a supression of relapses or by reducing significantly their frequency. No biological changes were observed and the clinical tolerance of the drug was excellent in most cases. This drug constitutes a variable alternative to lithium treatment, and lacks the well known lithium side effects and limitations.
基于对32例已知频率呈现情绪周期性变化患者的长期研究结果,作者得出结论:二丙基乙酰胺可通过抑制复发或显著降低复发频率,使约70%的患者情绪稳定。未观察到生物学变化,且该药物在大多数情况下临床耐受性良好。这种药物是锂盐治疗的一种可变替代方案,且没有锂盐众所周知的副作用和局限性。