Peterson Elisha E, Yao Caylynn, Sule Sangeeta D, Finkel Julia C
Division of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, Washington, DC, USA.
School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Case Rep Pediatr. 2022 Apr 8;2022:8717818. doi: 10.1155/2022/8717818. eCollection 2022.
Fibromyalgia (FM) is a noninflammatory disorder of the nervous system characterized by widespread musculoskeletal pain and somatic complaints of at least 3 months duration. There are no current diagnostic criteria for fibromyalgia in children to guide clinicians in recognition, thus leading to many subspecialty referrals and extensive imaging and tests. The purpose of this retrospective review is to compare two diagnostic criteria for juvenile fibromyalgia.
A retrospective chart review of 20 children diagnosed with juvenile fibromyalgia from a singular pain physician practice was performed. Both the Yunus diagnostic criteria and the 2016 American College of Rheumatology (ACR) diagnostic criteria were applied and compared.
85% of patients met criteria for fibromyalgia under both criteria. 15% of patients met only ACR criteria as the Yunus criteria excluded those with underlying conditions. Of the children who fulfilled criteria with use of both diagnostic tools, this cohort reported a high somatic symptom burden as demonstrated by the ACR symptom severity scales of 12 and satisfaction of at least 4 Yunus and Masi minor criteria on average. Widespread pain was noted with an ACR Widespread Pain Index (WPI) of 7, and tender points were 4.8 on average across the cohort. Effective therapeutic regimens among patients varied widely from medical monotherapy to multimodal treatment. Patients presented with pain for 1.8 yrs on average prior to a diagnosis. All of the cohort had a normal laboratory evaluation; half the cohort received additional imaging and testing.
This case series suggests the need for an updated diagnostic tool for pediatric fibromyalgia to facilitate recognition and treatment.
纤维肌痛(FM)是一种神经系统的非炎症性疾病,其特征为广泛的肌肉骨骼疼痛和至少持续3个月的躯体不适。目前尚无针对儿童纤维肌痛的诊断标准来指导临床医生进行识别,从而导致许多专科转诊以及广泛的影像学检查和测试。本回顾性研究的目的是比较两种青少年纤维肌痛的诊断标准。
对一位疼痛科医生诊所确诊的20例青少年纤维肌痛患儿进行回顾性病历审查。应用并比较了尤努斯诊断标准和2016年美国风湿病学会(ACR)诊断标准。
85%的患者符合两种标准下的纤维肌痛诊断标准。15%的患者仅符合ACR标准,因为尤努斯标准排除了有潜在疾病的患者。在使用两种诊断工具均符合标准的儿童中,该队列报告了较高的躯体症状负担,如ACR症状严重程度量表评分为12,平均至少满足4项尤努斯和马西次要标准。观察到广泛疼痛,ACR广泛疼痛指数(WPI)为7,全队列平均压痛点为4.8。患者中有效的治疗方案差异很大,从单一药物治疗到多模式治疗。患者在确诊前平均疼痛1.8年。所有队列的实验室检查均正常;一半队列接受了额外的影像学检查和测试。
本病例系列表明需要一种更新的儿童纤维肌痛诊断工具,以促进识别和治疗。