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青少年纤维肌痛综合征(JFMS):一种定义不明确的病症。

The juvenile fibromyalgia syndrome (JFMS): a poorly defined disorder.

作者信息

De Sanctis Vincenzo, Abbasciano Vincenzo, Soliman Ashraf T, Soliman Nada, Di Maio Salvatore, Fiscina Bernadette, Kattamis Christos

机构信息

Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy.

出版信息

Acta Biomed. 2019 Jan 23;90(1):134-148. doi: 10.23750/abm.v90i1.8141.

DOI:10.23750/abm.v90i1.8141
PMID:30889168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6502146/
Abstract

Juvenile fibromyalgia syndrome (JFMS) is a chronic condition characterized by symptoms of chronic diffuse musculoskeletal pain and multiple painful tender points on palpation. It is often accompanied by fatigue, disorders of sleep, chronic headaches, irritable bowel syndrome, and subjective soft tissue swelling. The complexity of the presenting clinical picture in JPFS has not been sufficiently defined in the literature. Similarities to adult fibromyalgia syndrome in JFMS are often difficult to compare, because many of the symptoms are "medically unexplained" and often overlap frequently with other medical conditions. However, a valid diagnosis of JFMS often decreases parents' anxiety, reduces unnecessary further investigations, and provides a rational framework for a management plan. The diagnostic criteria proposed by Yunus and Masi in 1985 to define JFMS were never validated or critically analyzed. In most cases, the clinical diagnosis is based on the history, the physical examination that demonstrates general tenderness (muscle, joints, tendons), the absence of other pathological conditions that could explain pain and fatigue, and the normal basic laboratory tests. Research and clinical observations defined that JFMS may have a chronic course that impacts the functional status and the psychosocial development of children and adolescents. This paper briefly reviews the existing knowledge on JFMS focusing on the diagnosis, clinical and the epidemiological characteristics in children and adolescents for better understanding of this disorder.

摘要

青少年纤维肌痛综合征(JFMS)是一种慢性疾病,其特征为慢性弥漫性肌肉骨骼疼痛以及触诊时有多个疼痛压痛点。它常伴有疲劳、睡眠障碍、慢性头痛、肠易激综合征以及主观的软组织肿胀。JPFS中呈现的临床症状的复杂性在文献中尚未得到充分界定。JFMS与成人纤维肌痛综合征的相似性往往难以比较,因为许多症状“医学上无法解释”,且常与其他病症频繁重叠。然而,对JFMS做出有效的诊断通常会减轻家长的焦虑,减少不必要的进一步检查,并为管理计划提供一个合理的框架。1985年Yunus和Masi提出的用于定义JFMS的诊断标准从未得到验证或批判性分析。在大多数情况下,临床诊断基于病史、显示全身压痛(肌肉、关节、肌腱)的体格检查、不存在可解释疼痛和疲劳的其他病理状况以及正常的基础实验室检查。研究和临床观察表明,JFMS可能有一个慢性病程,会影响儿童和青少年的功能状态及心理社会发展。本文简要回顾了关于JFMS的现有知识,重点关注儿童和青少年的诊断、临床及流行病学特征,以便更好地理解这种疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a3/6502146/a2afbb11d9dd/ACTA-90-134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a3/6502146/5f1f6991c27e/ACTA-90-134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a3/6502146/a2afbb11d9dd/ACTA-90-134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a3/6502146/5f1f6991c27e/ACTA-90-134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a3/6502146/a2afbb11d9dd/ACTA-90-134-g002.jpg

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