表现为嗜酸性粒细胞性胃肠炎和裂片样出血的高嗜酸性粒细胞综合征：一例报告。
Hypereosinophilic syndrome presenting as eosinophilic gastroenteritis disorder and splinter hemorrhages: A case report.
作者信息
Bhasi Ankith, Patnaik Itish, Panda Prasan Kumar, Singh Ashok
机构信息
Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh 249203, Uttarakhand, India.
Department of Gastroenterology, All India Institute of Medical Sciences, Rishikesh 249203, India.
出版信息
World J Gastrointest Pharmacol Ther. 2022 Mar 5;13(2):23-29. doi: 10.4292/wjgpt.v13.i2.23.
BACKGROUND
Eosinophilia and related organ damage are extensively studied hot topics among rare disorders. Any addition to the cohort of available case reports of the same will be adding knowledge for better management of this less known entity.
CASE SUMMARY
In this article, we describe a 27-year-old Indo-Aryan man who presented with abdominal pain, abdominal distension, and loose stools for variable days. He had splinter hemorrhages in the majority of fingernails. He was diagnosed with predominant eosinophilic gastrointestinal involvement with bowel obstruction and ascites, and was managed with intravenous immunoglobulin. He was subsequently treated with oral low dose steroid therapy and responded completely.
CONCLUSION
Our experience is evidence that prompt management of this hypereosinophilic lethal gastrointestinal (all three layers) infiltrative disease provides a cure and avoids complications. Splinter nail hemorrhages may be seen in the same disease.
背景
嗜酸性粒细胞增多症及相关器官损害是罕见疾病中广泛研究的热点话题。该疾病现有病例报告队列中的任何新增病例都将为更好地管理这一鲜为人知的疾病增添知识。
病例摘要
在本文中，我们描述了一名27岁的印度 - 雅利安男性，他出现腹痛、腹胀和腹泻症状达数日。他的大多数指甲出现裂片样出血。他被诊断为以嗜酸性粒细胞为主的胃肠道受累并伴有肠梗阻和腹水，接受了静脉注射免疫球蛋白治疗。随后他接受了口服低剂量类固醇治疗，并完全康复。
结论
我们的经验证明，对这种嗜酸性粒细胞增多性致死性胃肠道（三层）浸润性疾病进行及时治疗可治愈疾病并避免并发症。裂片样指甲出血可能出现在同一疾病中。
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