Ding Yi-Zong, Tang Dao-Qiang, Zhao Xiao-Jing
Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Department of Pathology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
World J Clin Cases. 2022 Mar 16;10(8):2604-2609. doi: 10.12998/wjcc.v10.i8.2604.
Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin's lymphoma (NHL). MCL frequently affects extranodal sites while endobronchial involvement is uncommon. Only 5 cases of MCL with endobronchial involvement have been previously reported.
A 56-year-old male patient arrived at the hospital complaining of a dry cough. A mass in the right upper lobe of the lung was revealed in Chest computed tomography (CT). Right lung hilar and mediastinal lymphadenopathies were also found by CT scan. The patient was diagnosed with central-type lung cancer with multiple lymph node metastases after positron emission tomography (PET) CT scan examination. The fiber optic bronchoscope examination revealed diffuse neoplasm infiltration in the inlet of the right up lobar bronchus. The patient was finally diagnosed with MCL based on the bronchoscopy and mediastinoscopy biopsy results.
MCL could masquerade as central type lung cancer. An endobronchial biopsy examination is necessary for the early diagnosis of MCL.
套细胞淋巴瘤(MCL)是非霍奇金淋巴瘤(NHL)的一种亚型。MCL常累及结外部位,而支气管内受累并不常见。此前仅报道过5例支气管内受累的MCL病例。
一名56岁男性患者因干咳入院。胸部计算机断层扫描(CT)显示右肺上叶有一肿块。CT扫描还发现右肺门和纵隔淋巴结肿大。正电子发射断层扫描(PET)CT扫描检查后,该患者被诊断为中央型肺癌伴多发淋巴结转移。纤维支气管镜检查显示右肺上叶支气管入口处有弥漫性肿瘤浸润。根据支气管镜检查和纵隔镜活检结果,该患者最终被诊断为MCL。
MCL可伪装成中央型肺癌。支气管内活检检查对于MCL的早期诊断是必要的。