Faculty of Environment and Life, Beijing University of Technology, Beijing, HE, China.
Electromagn Biol Med. 2022 Jul 3;41(3):272-280. doi: 10.1080/15368378.2022.2065680. Epub 2022 Apr 19.
: In order to study the effect of bifurcation vessels parameters on the temperature field and coagulation zone of microwave ablation on lung tissue. : The finite element method was used to establish the simulation model. The angle of bifurcation vessel model was 60°. The position of the antenna and the main blood vessel are parallel, and the distance between them was 5, 10 and 15 mm, respectively. Temperature field distribution was obtained at 2450 MHz, 50 W and 300 s. The blood flow velocity was set to 0.1 and 0.2 m/s. : The results showed when the antenna was 5 mm away from the bifurcation vessel and the velocity was 0.1 m/s, the position of x = 8.4 mm achieved the complete necrosis at 220 s, while the fraction of necrotic tissue at the symmetry point x = 1.6 mm was 0.2 at 300 s. For the distance was 10 mm and the velocity was 0.1 m/s, the fraction of necrotic tissue at x = 3 mm that near the bifurcation vessel was 0.53 and was 0.69 at the symmetry point x = 17 mm. When the antenna is 15 mm away from the vessel, the fraction of necrotic tissue of symmetrical points on both sides of the antenna obtained after ablation were the same. : The distance between the antenna and the bifurcation vessel over 15 mm, the blood flow has no effect on the coagulation zone. Besides, the distance between bifurcation vessel and antenna possesses a greater influence on the temperature distribution and coagulation zone than the blood flow velocity.
为了研究分支血管参数对肺组织微波消融的温度场和凝固区的影响。采用有限元法建立模拟模型。分支血管模型的角度为 60°。天线和主血管的位置平行,它们之间的距离分别为 5、10 和 15 毫米。在 2450MHz、50W 和 300s 时获得温度场分布。血流速度设置为 0.1 和 0.2m/s。结果表明,当天线距离分支血管 5mm 且速度为 0.1m/s 时,在 220s 时 x=8.4mm 处达到完全坏死,而在 300s 时 x=1.6mm 处对称点的坏死组织分数为 0.2。当距离为 10mm 且速度为 0.1m/s 时,靠近分支血管的 x=3mm 处的坏死组织分数为 0.53,在对称点 x=17mm 处为 0.69。当天线距离血管 15mm 时,消融后天线两侧对称点的坏死组织分数相同。距离天线大于 15mm 的分支血管,血流对凝固区没有影响。此外,分支血管与天线之间的距离对温度分布和凝固区的影响大于血流速度。