Cognitive Neuroscience Laboratory, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.
Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), University of Göttingen, Göttingen, Germany.
Sci Data. 2022 Apr 19;9(1):182. doi: 10.1038/s41597-022-01239-z.
Establishing the cortical neural representation of visual stimuli is a central challenge of systems neuroscience. Publicly available data would allow a broad range of scientific analyses and hypothesis testing, but are rare and largely focused on the early visual system. To address the shortage of open data from higher visual areas, we provide a comprehensive dataset from a neurophysiology study in macaque monkey visual cortex that includes a complete record of extracellular action potential recordings from the extrastriate medial superior temporal (MST) area, behavioral data, and detailed stimulus records. It includes spiking activity of 172 single neurons recorded in 139 sessions from 4 hemispheres of 3 rhesus macaque monkeys. The data was collected across 3 experiments, designed to characterize the response properties of MST neurons to complex motion stimuli. This data can be used to elucidate visual information processing at the level of single neurons in a high-level area of primate visual cortex. Providing open access to this dataset also promotes the 3R-principle of responsible animal research.
建立视觉刺激的皮质神经表示是系统神经科学的一个核心挑战。公开可用的数据将允许广泛的科学分析和假设检验，但它们很少且主要集中在早期视觉系统上。为了解决来自更高视觉区域的开放数据短缺问题，我们提供了一份来自猕猴视觉皮层神经生理学研究的综合数据集，其中包括来自外侧上颞（MST）区域的细胞外动作电位记录的完整记录、行为数据和详细的刺激记录。它包括 3 只恒河猴的 4 个半球的 139 个实验中记录的 172 个单个神经元的尖峰活动。该数据是在 3 个实验中收集的，旨在描述 MST 神经元对复杂运动刺激的反应特性。该数据集可用于阐明灵长类动物视觉皮层高级区域中单神经元的视觉信息处理。提供对该数据集的开放访问也促进了负责任的动物研究的 3R 原则。
