Prayag Parikshit S, Purandare Bharat D, Patwardhan Sampada A, Pairaiturkar Pradyumna P, Rege Amol J, Bhave Arvind V, S Ramya, Panchakshari Shweta P, Raja Poorana T, Melinkeri Advait S, Prayag Amrita P
Department of Infectious Diseases, Deenanath Mangeshkar Hospital, Pune, India.
Department of Microbiology, Deenanath Mangeshkar Hospital, Pune, India.
Indian J Orthop. 2022 Apr 15;56(7):1268-1276. doi: 10.1007/s43465-022-00633-4. eCollection 2022 Jul.
Coronavirus Disease (COVID-19) associated fungal infections including pulmonary aspergillosis, mucormycosis and other invasive fungal infections have been increasingly described in the current pandemic. osteomyelitis is a rare clinical form of aspergillosis. Most cases of osteomyelitis are reported in immunocompromised patients. We describe four cases of vertebral osteomyelitis caused by species in the post COVID-19 setting. To the best of our knowledge, vertebral osteomyelitis has not been described in the post COVID-19 setting. None of the four patients described in this series were immunocompromised and all of them had received steroids during their hospitalization for COVID-19 pneumonitis. Vertebral osteomyelitis caused by species is a rare clinical manifestation of Aspergillosis. It requires a high index of suspicion and prompt efforts to establish a diagnosis. For a clinician involved in assessing a patient with Spondylodiscitis, the work up must not be limited to testing for Tuberculosis. Every attempt must be made to establish the microbiological diagnosis. Combined medical and surgical management is generally needed for osteomyelitis.
在当前这场大流行中，与冠状病毒病（COVID-19）相关的真菌感染，包括肺曲霉病、毛霉病和其他侵袭性真菌感染，越来越多地被报道。骨髓炎是曲霉病一种罕见的临床形式。大多数骨髓炎病例报告见于免疫功能低下患者。我们描述了4例在COVID-19感染后发生的由 种引起的椎体骨髓炎病例。据我们所知，尚未有在COVID-19感染后发生椎体骨髓炎的相关描述。本系列中描述的4例患者均无免疫功能低下情况，且他们在因COVID-19肺炎住院期间均接受过类固醇治疗。由 种引起的椎体骨髓炎是曲霉病一种罕见的临床表现。它需要高度的怀疑指数并迅速努力进行诊断。对于参与评估脊椎椎间盘炎患者的临床医生而言，检查工作不应局限于结核病检测。必须尽一切努力确立微生物学诊断。骨髓炎通常需要联合药物和手术治疗。
