Ouladlahsen Ahd, Jebbar Sanaa, Benkiran Laila, Marih Latifa, Sodqi Mustapha, Maha Soussi-Abdellaoui, Chefchaouini Zouhair, Idali Brahim, Zouhair Chaoui
Faculté de Médecine et de Pharmacie, Université Hassan II, Casablanca, Maroc.
Service des Maladies Infectieuses, Centre Hospitalier Universitaire Ibn Rochd, Casablanca, Maroc.
Pan Afr Med J. 2022 Jul 21;42:226. doi: 10.11604/pamj.2022.42.226.32841. eCollection 2022.
Sternal osteomyelitis due to aspergillosis is extremely rare. Among all cases of invasive aspergillosis reported in the literature, the incidence of osteomyelitis is less than 3%. Aspergillosis mainly affects immunosuppressed patients. Clinical and radiological manifestation is nonspecific. Contamination is primarily caused by inhaling spores, but it can also directly reach a vulnerable area after medical procedure. Diagnosis is often difficult and may take several weeks, in particular when aspergillosis is not suspected. Positive diagnosis is based on imaging tests but it is confirmed by anatomopathological and/or mycological examinations. Prognosis mainly depends on early administration of treatment. We here report the case of a 63-year-old diabetic patient with sternocostal osteomyelitis due to Aspergillus occurred after coronary angioplasty.
曲霉菌病所致的胸骨骨髓炎极为罕见。在文献报道的所有侵袭性曲霉菌病病例中，骨髓炎的发生率低于3%。曲霉菌病主要影响免疫功能低下的患者。其临床和影像学表现不具特异性。感染主要由吸入孢子引起，但也可能在医疗操作后直接到达易感染部位。诊断往往困难，可能需要数周时间，尤其是在未怀疑曲霉菌病的情况下。阳性诊断基于影像学检查，但需经解剖病理学和/或真菌学检查证实。预后主要取决于早期治疗。我们在此报告一例63岁糖尿病患者，在冠状动脉血管成形术后发生了由曲霉菌引起的胸肋骨髓炎。
