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急诊就诊后持续使用阿片类药物治疗腰痛。

Continued opioid use following an emergency department presentation for low back pain.

机构信息

Institute for Musculoskeletal Health, Sydney Local Health District, Sydney, New South Wales, Australia.

Sydney Musculoskeletal Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

出版信息

Emerg Med Australas. 2022 Oct;34(5):694-697. doi: 10.1111/1742-6723.13979. Epub 2022 Apr 20.

DOI:10.1111/1742-6723.13979
PMID:35441464
Abstract

OBJECTIVE

To investigate the proportion of patients with low back pain who receive an opioid analgesic prescription on hospital discharge, the proportion using opioid analgesics 4 weeks after discharge, and to identify predictors of continued opioid analgesic use at 4 weeks after an ED presentation in opioid-naïve patients.

METHODS

An observational cohort study nested within a randomised controlled trial in four EDs in New South Wales, Australia. Participants were adults who presented to the ED with non-specific low back pain or low back pain with lower limb neurological signs and symptoms. Electronic medical records supplemented the patient-reported pain and use of opioid analgesics at 4-week follow up.

RESULTS

Of the 104 patients included, 33 (31.7%, 95% confidence interval [CI] 22.9-41.6) received an opioid analgesic prescription at hospital discharge and 38 (36.5%, 95% CI 27.3-46.6) reported taking an opioid analgesic for pain 4 weeks after the ED presentation. Among opioid-naïve patients (n = 85), older age (odds ratio [OR] 1.04, 95% CI 1.00-1.08, P = 0.031) was the only predictor for continued opioid analgesic use at 4 weeks post-ED presentation.

CONCLUSION

About one-third of patients who present to the ED with low back pain receive an opioid analgesic prescription on discharge and are taking an opioid analgesic 4 weeks later. These findings justify future research to identify strategies to reduce the risk of long-term opioid use in patients who present to the ED with low back pain.

摘要

目的

调查出院时接受阿片类镇痛药处方、出院后 4 周内使用阿片类镇痛药的腰痛患者比例,并确定在 ED 就诊的阿片类药物初治患者中,4 周后继续使用阿片类药物的预测因素。

方法

这是一项在澳大利亚新南威尔士州四家急诊科进行的观察性队列研究,嵌套在一项随机对照试验中。参与者为因非特异性腰痛或腰痛伴下肢神经症状和体征就诊急诊科的成年人。电子病历补充了患者在 4 周随访时报告的疼痛和阿片类镇痛药的使用情况。

结果

在纳入的 104 名患者中,33 名(31.7%,95%置信区间[CI] 22.9-41.6)在出院时接受了阿片类镇痛药处方,38 名(36.5%,95% CI 27.3-46.6)报告在 ED 就诊后 4 周内使用阿片类镇痛药缓解疼痛。在阿片类药物初治患者(n=85)中,年龄较大(优势比[OR] 1.04,95% CI 1.00-1.08,P=0.031)是 ED 就诊后 4 周继续使用阿片类药物的唯一预测因素。

结论

约三分之一因腰痛就诊急诊科的患者在出院时接受阿片类镇痛药处方,并且在 4 周后仍在使用阿片类镇痛药。这些发现为未来研究确定减少因腰痛就诊急诊科的患者长期使用阿片类药物的风险策略提供了依据。

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