Brown University School of Public Health, Department of Epidemiology, Box G-121-3, Providence, RI 02912, USA.
Emergency Medicine, University of California, San Francisco, San Francisco, CA, USA.
Am J Emerg Med. 2020 Oct;38(10):2119-2124. doi: 10.1016/j.ajem.2020.07.016. Epub 2020 Jul 10.
Previous research has suggested caution about opioid analgesic usage in the emergency department (ED) setting and raised concerns about variations in prescription opioid analgesic usage, both across institutions and for whom they are prescribed. We examined opioid analgesic usage in ED patients with suspected urolithiasis across fifteen participating hospitals.
This is a secondary analysis of a clinical trial including adult ED patients with suspected urolithiasis. In multilevel models accounting for clustering by hospital, we assessed demographic, clinical, state-level, and hospital-level factors associated with opioid analgesic administration during the ED visit and prescription at discharge.
Of 2352 participants, 67% received an opioid analgesic during the ED visit and 61% were prescribed one at discharge. Opioid analgesic usage varied greatly across hospitals, ranging from 46% to 88% (during visit) and 34% to 85% (at discharge). Hispanic patients were less likely than non-Hispanic white patients to receive opioid analgesics during the ED visit (OR 0.72, 95% CI 0.55-0.94). Patients with higher education (OR 1.29, 95% CI 1.05-1.59), health insurance coverage (OR 1.27, 95% CI 1.02-1.60), or receiving care in states with a prescription drug monitoring program (OR 1.64, 95% CI 1.06-2.53) were more likely to receive an opioid analgesic prescription at ED discharge.
We found marked hospital-level differences in opioid analgesic administration and prescribing, as well as associations with education, healthcare insurance, and race/ethnicity groups. These data might compel clinicians and hospitals to examine their opioid use practices to ensure it is congruent with accepted medical practice.
先前的研究表明,在急诊科(ED)环境中使用阿片类镇痛药需要谨慎,并对处方阿片类镇痛药的使用存在差异表示担忧,包括不同机构之间以及为谁开处方的差异。我们检查了在 15 家参与医院的疑似尿路结石的 ED 患者中阿片类镇痛药的使用情况。
这是一项包括疑似尿路结石的成年 ED 患者的临床试验的二次分析。在考虑到医院聚类的多水平模型中,我们评估了与 ED 就诊期间开处阿片类镇痛药和出院时开处处方相关的人口统计学、临床、州级和医院级因素。
在 2352 名参与者中,67%在 ED 就诊期间接受了阿片类镇痛药,61%在出院时开处了此类药物。阿片类镇痛药的使用在医院之间差异很大,范围从 46%到 88%(就诊期间)和 34%到 85%(出院时)。与非西班牙裔白人患者相比,西班牙裔患者在 ED 就诊期间接受阿片类镇痛药的可能性较低(OR 0.72,95%CI 0.55-0.94)。受教育程度较高(OR 1.29,95%CI 1.05-1.59)、有医疗保险(OR 1.27,95%CI 1.02-1.60)或在有处方药物监测计划的州接受治疗(OR 1.64,95%CI 1.06-2.53)的患者,更有可能在 ED 出院时开处阿片类镇痛药处方。
我们发现,在阿片类镇痛药的管理和处方方面存在明显的医院水平差异,并且与教育、医疗保健保险和种族/民族群体有关。这些数据可能促使临床医生和医院检查他们的阿片类药物使用情况,以确保其符合公认的医疗实践。