Dave Bharat R, Marathe Nandan, Mayi Shivanand, Degulmadi Devanand, Rai Ravi Ranjan, Patil Sameer, Jadav Kirit, Bali Shiv K, Kumar Arvind, Meena Umesh, Parmar Vatsal, Amin Prarthan, Dave Mirant, Krishnan Preety Ajay, Krishnan Ajay
Stavya Spine Hospital & Research Institute, Ahmedabad, Gujarat, India.
Global Spine J. 2024 Jan;14(1):93-100. doi: 10.1177/21925682221095467. Epub 2022 Apr 20.
Prospective, observational.
The aim of our study was to assess the amount of reduction in lean muscle mass (LMM) of multifidus muscle (MFM) between conventional open Transforaminal lumbar interbody fusion (CO-TLIF) as compared to Minimally invasive spine Transforaminal lumbar interbody fusion (MIS-TLIF).
This study was conducted between 2017 and 2020. It included 100 patients divided into two groups, 50 patients treated with CO-TLIF, 50 treated with MIS-TLIF. Only patients undergoing single level, primary lumbar fusion at L4-5 or L5-S1 level for degenerative pathologies were included. All patients were assessed by magnetic resonance imaging (MRI) scans 1-year post surgery. Measurements were performed using ImageJ image processing program.
Mean percentage reduction in LMM in CO-TLIF group was 45.52 ± 12.36% and MIS-TLIF group was 25.83 ± 9.64% [statistically significant (t = 8.78, < .001)]. Mean percentage reduction in LMM on side of cage insertion was 39.63 ± 15.96% and opposite side was 31.40 ± 15.01% [statistically significant (t = 9.06, < .001)]. Mean reduction of LMM among males was 29.38 ± 15.23% and females was 40.42 ± 12.67% [statistically significant (t = -3.95, < .001)].We observed significant but weak degree of correlation between age and percentage reduction of LMM (r = .22, = .028).
Mean reduction in LMM was greater in CO-TLIF group as compared to MIS-TLIF. There was greater reduction in LMM in females and on side of cage insertion. We also found greater reduction in LMM with increasing age in both groups.
前瞻性观察研究。
我们研究的目的是评估传统开放性经椎间孔腰椎椎体间融合术(CO-TLIF)与微创脊柱经椎间孔腰椎椎体间融合术(MIS-TLIF)相比,多裂肌(MFM)的瘦肌肉量(LMM)减少量。
本研究于2017年至2020年进行。它包括100例患者,分为两组,50例接受CO-TLIF治疗,50例接受MIS-TLIF治疗。仅纳入因退行性病变在L4-5或L5-S1节段接受单节段、初次腰椎融合术的患者。所有患者在术后1年通过磁共振成像(MRI)扫描进行评估。使用ImageJ图像处理程序进行测量。
CO-TLIF组LMM的平均减少百分比为45.52±12.36%,MIS-TLIF组为25.83±9.64%[具有统计学意义(t = 8.78,P <.001)]。椎间融合器置入侧LMM的平均减少百分比为39.63±15.96%,对侧为31.40±15.01%[具有统计学意义(t = 9.06,P <.001)]。男性LMM的平均减少量为29.38±15.23%,女性为40.42±12.67%[具有统计学意义(t = -3.95,P <.001)]。我们观察到年龄与LMM减少百分比之间存在显著但较弱的相关性(r =.22,P =.028)。
与MIS-TLIF相比,CO-TLIF组LMM的平均减少量更大。女性以及椎间融合器置入侧的LMM减少量更大。我们还发现两组中LMM随着年龄增长减少量更大。