Martins Gabriela Parússolo, Sandy Natascha Silva, Alvarenga Lucas Rocha, Lomazi Elizete Aparecida, Bellomo-Brandão Maria Angela
Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP, Brasil.
University of Toronto, Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canadá.
Arq Gastroenterol. 2022 Jan-Mar;59(1):97-101. doi: 10.1590/S0004-2803.202200001-17.
Chronic abdominal pain (CAP) carries a significant burden of disease. The last edition of the Rome Criteria (Rome IV) allows the diagnosis of functional gastrointestinal disorders (FGIDs) according to symptoms-based criteria; however, patients continue to experience a delay in their diagnosis and to be submitted to different interventions before the establishment of a positive diagnosis.
We aimed to characterize etiology, clinical features, and interventions in a pediatric cohort of patients with CAP secondary to FGIDs, who were referred to our tertiary care university-affiliated hospital, in Brazil.
A retrospective descriptive study of children and adolescents (aged 20 years and younger) referred to our institution, from January/2013 to December/2018, for CAP, and who fulfilled criteria for FGIDs classified according to Rome IV criteria.
Three hundred twenty-eight patients with CAP were screened, of which 67.9% (223 patients) fulfilled the criteria for FGIDs and were included in the study. Sixty percent were female, with a mean age of 8.3 years. At the time of referral, the mean duration of symptoms was 2.8 years. Length/height for age and weight for age mean z-scores were -0.08±1.87 and -0.38±1.62, respectively. Functional abdominal pain not otherwise specified was overall the most common diagnosis (70.4%). Before establishing the diagnosis of FGIDs, multiple pharmacological interventions were described, while after, the mainstay of therapy was education/reassurance and dietary interventions. Thirty-two percent of patients did not further require specialized follow-up.
Even at the tertiary care level, FGIDs were still the most common etiology of chronic abdominal pain, particularly functional abdominal pain not otherwise specified. Despite the relatively long duration of symptoms at referral, cessation of specialized care follow-up was possible in approximately a third of the cases.
慢性腹痛(CAP)带来了重大的疾病负担。最新版的罗马标准(罗马IV)允许根据基于症状的标准诊断功能性胃肠疾病(FGIDs);然而,患者在诊断上仍会出现延迟,并且在确诊之前会接受不同的干预措施。
我们旨在描述继发于FGIDs的CAP儿科患者队列的病因、临床特征和干预措施,这些患者被转诊至巴西一所大学附属三级医疗机构。
对2013年1月至2018年12月转诊至我院的儿童和青少年(20岁及以下)进行回顾性描述性研究,这些患者患有CAP,并符合根据罗马IV标准分类的FGIDs标准。
对328例CAP患者进行了筛查,其中67.9%(223例患者)符合FGIDs标准并纳入研究。60%为女性,平均年龄8.3岁。转诊时,症状的平均持续时间为2.8年。年龄别身长/身高和年龄别体重的平均z值分别为-0.08±1.87和-0.38±1.62。未另行指定的功能性腹痛总体上是最常见的诊断(70.4%)。在确立FGIDs诊断之前,描述了多种药物干预措施,而之后,治疗的主要手段是教育/安抚和饮食干预。32%的患者不再需要专门的随访。
即使在三级医疗水平,FGIDs仍是慢性腹痛最常见的病因,尤其是未另行指定的功能性腹痛。尽管转诊时症状持续时间相对较长,但约三分之一的病例有可能停止专门的随访。