Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin,
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
WMJ. 2022 Apr;121(1):61-63.
Laboratory investigations pursued for infants with failure to thrive (FTT) often show mild transaminase elevations, the incidence and significance of which are unknown.
This retrospective chart review included infants diagnosed with simple nutritional FTT at a single academic tertiary care system. Comparisons of diagnostic studies and outcomes between children with and without transaminase elevation were performed using chi-square and Wilcoxon rank sum tests.
None of the infants with abnormal transaminases required additional follow-up or developed alternative diagnoses in the following year.
Transaminase elevation may be common in infants with FTT and may not warrant further investigation if the history indicates an isolated etiology of insufficient nutrition.
对生长发育迟缓（FTT）婴儿进行的实验室检查常显示出轻微的转氨酶升高，但这种升高的发生率和意义尚不清楚。
本回顾性图表研究纳入了在单一学术性三级医疗系统中被诊断为单纯性营养性 FTT 的婴儿。使用卡方检验和 Wilcoxon 秩和检验比较转氨酶升高与不升高患儿的诊断性研究和结局。
无任何转氨酶异常的婴儿在随后的 1 年中需要进一步随访或出现其他诊断。
转氨酶升高可能在 FTT 婴儿中很常见，如果病史提示仅为营养不足这一单一病因，则可能无需进一步检查。
