Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin,
Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
WMJ. 2022 Apr;121(1):E5-E9.
Reports of extraintestinal manifestations of () infections are rare. The frequency of these infections comprises approximately 0.17% to 0.6% of all infections. While they are becoming more frequent worldwide, the precise trend is unclear.
An 83-year-old female patient presented with pleuritic chest pain 2 to 3 months after a needle biopsy of her liver abscess confirmed . She was found to have extension of the liver abscess into the chest cavity, leading to empyema, and was treated with intravenous antimicrobials.
This is the fifth known reported case of leading to a pyogenic liver abscess and the first case where the liver abscess was associated with an empyema. While long-term metronidazole is considered effective for managing extra intestinal infection, our patient was treated with vancomycin and meropenem.
To determine epidemiology and a proper treatment regimen for extraintestinal C difficile infection, a greater accumulation of cases is necessary.
()感染的肠外表现报告罕见。这些感染的频率约占所有感染的 0.17%至 0.6%。虽然它们在全球范围内变得越来越常见,但确切的趋势尚不清楚。
一名 83 岁女性患者在肝脓肿的针吸活检后 2 至 3 个月出现胸痛,经证实为 感染。她的肝脓肿扩展到胸腔,导致脓胸,并接受了静脉内抗菌药物治疗。
这是第五个已知的导致化脓性肝脓肿的 感染病例,也是第一个与脓胸相关的 感染病例。虽然长期使用甲硝唑被认为对治疗肠外艰难梭菌感染有效,但我们的患者接受了万古霉素和美罗培南治疗。
为了确定肠外艰难梭菌感染的流行病学和适当的治疗方案,需要积累更多的病例。