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早期烧伤切痂与植皮

Early burn excision and grafting.

作者信息

Heimbach D M

出版信息

Surg Clin North Am. 1987 Feb;67(1):93-107. doi: 10.1016/s0039-6109(16)44135-6.

Abstract

The current state of knowledge and experience with early burn wound closure leads to some conclusions that are proved and others that are suggested. The issues that are proved include the following: Small (less than 20 per cent TBSA) full-thickness burns and indeterminate (deep partial-thickness versus full-thickness) burns, if treated by an experienced surgeon, can be excised safely and grafted with a decrease in hospital stay, cost to the patient, and time away from work or school. Early excision and grafting dramatically decreases the number of painful ward debridements required by all patients. Patients with burns between 20 and 40 per cent TBSA appear to have fewer infectious wound complications and a shortened hospital stay if treated with early excision and grafting. In addition to the above conclusions, about which there is little disagreement, there are other suggestive data and clinical impressions that do not yet have "hard data" to support them. These issues include the following: Scarring is less in wounds closed early, leading to better appearance and the need for fewer reconstructive procedures. There presently is not a good measure of "cosmetic appearance," and comparative studies await an acceptable scale to measure results. Mortality from wound infection is less in patients with major burns. Because wounds exceeding the donor sites cannot be closed permanently and completely until donor sites can be reharvested, proof will come only when a durable permanent cover can be applied in a timely fashion. Data now suggest that mortality has decreased, but none of the studies has been conclusive. Mortality from other complications of major burns may decrease with early excision and grafting. Decreasing stress, hypermetabolism, and decreasing the overall bacterial load of such patients enables them to resist other complications better. The only present data supporting this conclusion, however, come from animal studies. The current state of the art suggests that small, deep burns can be excised and grafted by general or plastic surgeons in community hospitals as long as they are interested in the procedure and the hospital has the proper support facilities. Burns of cosmetically or functionally important areas (face, hands, feet, and joints) should be excised by someone with a special interest in burns, and burns in excess of 10 per cent TBSA should be excised only in facilities with excellent support facilities, including an experienced anesthesiologist, trained nursing personnel, good critical-care facilities, and a safe blood bank.

摘要

早期烧伤创面闭合的现有知识和经验得出了一些已被证实的结论以及其他一些有待进一步证实的结论。已被证实的问题包括:小面积(小于20%体表面积)的全层烧伤和不确定深度(深二度与全层烧伤)的烧伤,如果由经验丰富的外科医生治疗,可以安全地进行切除并植皮,从而缩短住院时间、降低患者费用以及减少误工或误学时间。早期切除和植皮显著减少了所有患者所需的痛苦的病房清创次数。20%至40%体表面积烧伤的患者如果接受早期切除和植皮治疗,似乎感染性伤口并发症更少,住院时间更短。除了上述几乎没有争议的结论外,还有其他一些提示性数据和临床印象,但尚无“确凿数据”支持。这些问题包括:早期闭合的伤口瘢痕形成较少,外观更好,所需的重建手术也更少。目前还没有一个很好的“美容外观”衡量标准,比较研究有待一个可接受的量表来衡量结果。大面积烧伤患者因伤口感染导致的死亡率较低。由于在供皮区能够再次取皮之前,超过供皮区面积的伤口无法永久完全闭合,只有在能够及时应用持久的永久覆盖物时才能得到证实。目前的数据表明死亡率有所下降,但没有一项研究是结论性的。大面积烧伤的其他并发症导致的死亡率可能会随着早期切除和植皮而降低。减轻此类患者的应激、高代谢状态以及降低总体细菌负荷,能使他们更好地抵抗其他并发症。然而,目前支持这一结论的唯一数据来自动物研究。目前的技术水平表明,只要社区医院的普通外科或整形外科医生对该手术感兴趣且医院具备适当的支持设施,小面积深度烧伤就可以进行切除和植皮。美容或功能重要部位(面部、手部、足部和关节)的烧伤应由对烧伤有特殊兴趣的人员进行切除,超过10%体表面积的烧伤应仅在具备优秀支持设施的机构进行切除,这些设施包括经验丰富的麻醉医生、训练有素的护理人员、良好的重症监护设施以及安全的血库。

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