12214University of South Alabama College of Medicine, Mobile, AL, USA.
Department of Surgery, 12214University of South Alabama College of Medicine, Mobile, AL, USA.
Am Surg. 2022 Aug;88(8):1832-1837. doi: 10.1177/00031348221084956. Epub 2022 Apr 20.
Carbon dioxide pneumoperitoneum during laparoscopy changes cardiorespiratory physiology and contributes to post-op pain. We studied outcomes before and after implementing low-pressure pneumoperitoneum QI project.
Forty-two patients were insufflated at standard pressures (15 mmHg) while 41 were insufflated using low (8-12 mmHg) during laparoscopic procedures. These variables were obtained from the patient chart: pain scores, intravenous morphine milligram equivalents (MME), peak inspiratory pressures (PIP), end-tidal CO (EtCO), surgery duration, and patient demographics. The study was conducted after IRB approval.
Low-pressure pneumoperitoneum is feasible and the surgeon can increase to 10-12 mmHg as needed. The mean post-op IV MME was significantly decreased in the low-pressure group (11.75 ± 10.41) compared to the standard pressure group (17.36 ± 18.1) (t-test, = .047). Mean peak inspiratory pressures during insufflation were significantly higher for procedures conducted at standard pressure (31.40 ± 4.82) compared to the 8 mmHg (24.68 ± 4.19) and 12 mmHg (27.33± 3.85) low pressure groups (one-way ANOVA, < .0001). During insufflation, there was a significant increase in the average EtCO in the standard pressure group (42.07 ± 5.60) compared to the 8 mmHg low pressure group (37.59 ± 5.05) (ANOVA, = .0096). Constant flow insufflation was more likely to be performed at low pressure than demand mode (58% v. 33%).
Low pressure pneumoperitoneum decreases PIP pressure and CO2 absorption evidenced by lower ETCO2 intra-operatively. Patients have significant improvement in postoperative pain evidenced by decreased narcotics needed. Low pressure pneumoperitoneum using a constant flow insufflator is safe and results in improved patient outcomes.
腹腔镜手术中的二氧化碳气腹会改变心肺生理功能,并导致术后疼痛。我们研究了实施低压气腹质量改进项目前后的结果。
42 名患者在标准压力(15mmHg)下充气,41 名患者在腹腔镜手术中使用低压力(8-12mmHg)充气。这些变量从患者图表中获得:疼痛评分、静脉注射吗啡毫克当量(MME)、吸气峰压(PIP)、呼气末二氧化碳(EtCO)、手术持续时间和患者人口统计学。该研究在 IRB 批准后进行。
低压气腹是可行的,外科医生可以根据需要增加到 10-12mmHg。与标准压力组(17.36 ± 18.1)相比,低压组术后静脉注射 MME 明显降低(11.75 ± 10.41)(t 检验, =.047)。在标准压力下进行的手术中,吸气峰压在充气过程中明显较高(31.40 ± 4.82),而 8mmHg(24.68 ± 4.19)和 12mmHg(27.33± 3.85)的低压组(单向方差分析, <.0001)。在充气过程中,标准压力组的平均 EtCO 显著增加(42.07 ± 5.60),而 8mmHg 低压组的平均 EtCO 显著降低(37.59 ± 5.05)(ANOVA, =.0096)。与需求模式相比,恒流充气更可能在低压下进行(58%对 33%)。
低压气腹可降低 PIP 压力和 CO2 吸收,术中表现为较低的 EtCO2。患者术后疼痛明显改善,所需麻醉药减少。使用恒流注气的低压气腹安全,可改善患者预后。