Department of Ophthalmolgy, Health Science University Ankara Researching and Training Hospital, Ankara, Turkey.
Ocul Immunol Inflamm. 2023 May;31(4):760-767. doi: 10.1080/09273948.2022.2046791. Epub 2022 Apr 20.
To assess the different clinical findings and symptoms of patients with optic neuritis (ON) and uveitis, who were diagnosed with syphilis.
The medical records of patients, who had ocular involvement of syphilis, were retrospectively reviewed. Thirteen patients with syphilitic optic neuropathy (SON) were enrolled and underwent complete ophthalmological examinations and auxiliary laboratory testing.
Nine patients (69.2%) had comorbidities in addition to syphilis. One patient (with two eyes) presented with retrobulbar neuritis, and 12 patients (with 17 eyes) presented with anterior optic neuritis. Three patients (23.1%) had no uveitis, and 10 patients (76.9%) had uveitis in cases with SON. Four eyes (16.6%) had subretinal fluid, and three eyes (12.5%) had cystoid macular edema.
Visual function can be preserved with early diagnosis and proper treatment. Accordingly, newly diagnosed patients with ON and uveitis should undergo syphilitic investigation in routine practice.
评估诊断为梅毒的视神经炎（ON）和葡萄膜炎患者的不同临床发现和症状。
回顾性分析了眼部受累的梅毒患者的病历。共纳入 13 例梅毒性视神经病变（SON）患者，进行了全面的眼科检查和辅助实验室检查。
9 例患者（69.2%）除梅毒外还有合并症。1 例（双眼）表现为球后视神经炎，12 例（17 只眼）表现为前部视神经炎。3 例（23.1%）无葡萄膜炎，10 例（76.9%）有 SON 患者的葡萄膜炎。4 只眼（16.6%）有视网膜下液，3 只眼（12.5%）有囊样黄斑水肿。
早期诊断和适当治疗可以保留视力功能。因此，在常规实践中，对于新诊断的 ON 和葡萄膜炎患者，应进行梅毒检查。
