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感觉处理与 Prader-Willi 综合征中自闭症谱系障碍样行为的关系。

Relationship Between Sensory Processing and Autism Spectrum Disorder-Like Behaviors in Prader-Willi Syndrome.

机构信息

Sohei Saima, Hiroshi Ihara, Hiroyuki Ogata, Masao Gito, Nobuyuki Murakami, Yuji Oto, Atsushi Ishii, and Asami Takahashi, Dokkyo Medical University Saitama Medical Center, Japan.

Toshiro Nagai, Nakagawanosato Ryoiku Center, Japan. Sohei Saima and Hiroshi Ihara contributed equally to this article.

出版信息

Am J Intellect Dev Disabil. 2022 May 1;127(3):249-263. doi: 10.1352/1944-7558-127.3.249.

DOI:10.1352/1944-7558-127.3.249
PMID:35443050
Abstract

The relationship between sensory processing and ASD-like and associated behaviors in patients with Prader-Willi Syndrome (PWS) remains relatively unexplored. Examining this relationship, 51 adults with PWS were administered the Pervasive Developmental Disorders Autism Society Japan Rating Scale (PARS), Short Sensory Profile (SSP-J), Food-Related Problem Questionnaire (FRPQ), and Aberrant Behavior Checklist (ABC-J). Based on SSP-J z-scores, participants were classified into three severity groups. Analysis of variance was performed to compare the behavioral scores of these three groups. Statistically significant group differences were observed in PARS (p = .006, ηp2 = .194) and ABC-J (p = .006, ηp2 = .193) scores. Our findings suggest that the level of sensory processing may predict ASD-like and aberrant behaviors in adults with PWS, implying the importance of a proper assessment for early intervention.

摘要

感觉处理与 Prader-Willi 综合征(PWS)患者的 ASD 样和相关行为之间的关系仍相对未知。为了研究这种关系,对 51 名 PWS 成年人进行了广泛性发育障碍自闭症协会日本评定量表(PARS)、短感觉评估(SSP-J)、与食物相关的问题问卷(FRPQ)和异常行为检查表(ABC-J)的评估。根据 SSP-J 的 z 分数,参与者被分为三组严重程度。对这三组的行为评分进行方差分析。在 PARS(p =.006,ηp2 =.194)和 ABC-J(p =.006,ηp2 =.193)评分方面观察到了统计学上的显著组间差异。我们的研究结果表明,感觉处理水平可能预测 PWS 成人的 ASD 样和异常行为,这意味着早期干预需要进行适当的评估。

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