Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil.
Brazilian Centre for Evidence-Based Research (COBE), Federal University of Santa Catarina, Florianópolis, Brazil.
Sleep. 2022 Jul 11;45(7). doi: 10.1093/sleep/zsac073.
To evaluate the available evidence on the putative relationships between sleep bruxism (SB) and, obstructive sleep apnea (OSA) to assess the extent of research on this topic, and to formulate suggestions for future research.
A scoping review including studies examining temporal and overall association and prevalence of SB and OSA was performed. Six main databases and gray literature were searched. The studies selection was conducted by three independent reviewers. A narrative synthesis of the results was carried out.
Thirteen studies in adults and eight studies in children were finally included. The median of concomitant conditions prevalence was 39.3% in adults and 26.1% in children. Marked methodological variability was identified among studies in adults and even more when we compared detection methods in children. No significant association between OSA and SB emerged in most studies in adults, while an association may be possible in children.
Based on the current literature, it is not possible to confirm that there is a relationship between SB and OSA in adults. In patients under pediatric care, although this association seems plausible, there is currently insufficient supportive evidence. Standardized validated methodologies for identifying SB should be consistently used in both populations before reaching any conclusion regarding such association. Furthermore, assessment of shared phenotypes between patients with SB and patients with OSA may reveal new insights that will contribute to personalized approaches aiming to optimize the management of such comorbidities.
评估睡眠磨牙症 (SB) 和阻塞性睡眠呼吸暂停 (OSA) 之间可能存在的关系的现有证据，评估该主题的研究程度，并为未来的研究提出建议。
进行了一项范围综述，包括检查 SB 和 OSA 时间和总体关联以及患病率的研究。共检索了六个主要数据库和灰色文献。研究选择由三名独立审查员进行。对结果进行了叙述性综合。
最终纳入了 13 项成人研究和 8 项儿童研究。成人并发疾病患病率的中位数为 39.3%，儿童为 26.1%。在成人研究中发现了明显的方法学变异性，而在比较儿童的检测方法时甚至更多。大多数成人研究并未发现 OSA 和 SB 之间存在显著关联，而在儿童中可能存在关联。
根据目前的文献，不能确定成人中 SB 和 OSA 之间存在关系。在儿科患者中，虽然这种关联似乎合理，但目前缺乏足够的支持证据。在得出任何关于这种关联的结论之前，应在这两个群体中一致使用用于识别 SB 的标准化验证方法。此外，对患有 SB 和患有 OSA 的患者之间的共享表型进行评估可能会揭示新的见解，这将有助于针对这些合并症的个性化方法优化管理。
