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慢性阻塞性肺疾病稳定期和急性加重期患者的 Cat 评分的作用及其与 PFT 的相关性。

Usefulness of Cat Score in Patients with Stable Copd and Acute Exacerbation of Copd and it's Co-Relation with PFT.

机构信息

Navodaya Medical College, Raichur.

出版信息

J Assoc Physicians India. 2022 Apr;70(4):11-12.

Abstract

COPD was reported to be the 6th leading cause of death worldwide in the year 1990 and 4th in 2000. The CAT i.e. COPD Assessment Test was introduced in 2009 as an easy tool to assess health status impairment in COPD patients. The CAT evaluates severity that a patient experiences of many of the symptoms of COPD like breathlessness, cough, phlegm, etc. and is observed to be quite abnormal even in mild form of the disease. Hence it can be used as a simple tool to identify patients who are at increased risk of exacerbations. Material: All OPD and IPD patients coming to Navodaya Medical college Raichur, fulfilling the inclusion criteria i.e- Any patient with acute exacerbation of COPD diagnosed by clinical history and examination,any patient with Stable COPD and willing to participate were enrolled in the study. Patients with Interstitial Lung Diseases, Bronchial Asthma, History of Myocardial Infarction within 1 month, Chest or abdominal pain of any cause, oral or facial pain exacerbated by a mouthpiece, stress incontinence,dementia or confusional state, BMI > 25 kg/ m2 were excluded from the study. Sample size - Acute Exacerbation: Minimum 50 cases. Stable Disease: Minimum 50 cases. Appropriate statistical software, including but not restricted to MS Excel, SPSS ver. 20 were used for statistical analysis. Observation: The coefficient of correlation between CAT score and FEV1 (% predicted) in stable COPD cases is significant at 0.05 level of significance. The coefficient of correlation between CAT score and FEV1: FVC in stable COPD cases at 0.05 level of significance.The association between cases of Acute Exacerbation of COPD on Day 1 and Day 5 was significant between CAT scores, pulse rate, respiratory rate, FVC (%predicted) and FEV1 (%predicted) Conclusion: The CAT score provides a simple and reliable measure of overall COPD related health status for long term follow-up of an individual patient and their assessment. CAT score correlates well with PFT parameters in stable disease and during acute exacerbation. Hence it provides a reliable score of severity of the disease. In addition, the CAT score is cost effective, easy to use and is particularly useful for health settings where access to other objective measurements like spirometry is limited.

摘要

慢性阻塞性肺疾病(COPD)在 1990 年被列为全球第六大死亡原因,在 2000 年则上升至第四位。CAT 即 COPD 评估测试于 2009 年推出,作为评估 COPD 患者健康状况受损程度的简单工具。CAT 评估患者在呼吸困难、咳嗽、咳痰等多种 COPD 症状方面的严重程度,即使在疾病的轻度形式下也观察到相当异常。因此,它可以用作识别有加重风险的患者的简单工具。

材料

所有到拉杰布尔纳瓦达亚医学院就诊的 OPD 和 IPD 患者,满足纳入标准,即:任何经临床病史和检查诊断为 COPD 急性加重的患者,任何愿意参与的稳定期 COPD 患者均被纳入研究。排除患有间质性肺疾病、支气管哮喘、1 个月内心肌梗死病史、任何原因引起的胸痛或腹痛、因牙垫而加剧的口腔或面部疼痛、应激性尿失禁、痴呆或意识混乱、BMI>25kg/m2 的患者。

样本量

急性加重

至少 50 例。

稳定期疾病

至少 50 例。

适当的统计软件,包括但不限于 MS Excel、SPSS 版本 20 用于统计分析。

观察结果

在稳定期 COPD 患者中,CAT 评分与 FEV1(%预计值)之间的相关系数在 0.05 水平上具有统计学意义。在稳定期 COPD 患者中,CAT 评分与 FEV1/FVC 的相关系数在 0.05 水平上具有统计学意义。COPD 急性加重患者在第 1 天和第 5 天的 CAT 评分、脉搏率、呼吸率、FVC(%预计值)和 FEV1(%预计值)之间的相关性具有统计学意义。

结论

CAT 评分可作为个体患者长期随访和评估的一种简单、可靠的 COPD 相关健康状况指标。CAT 评分与稳定期疾病和急性加重期间的 PFT 参数相关性良好。因此,它提供了一种可靠的疾病严重程度评分。此外,CAT 评分具有成本效益,易于使用,在其他客观测量(如肺活量计)有限的卫生环境中特别有用。

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