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共识引导的推荐意见支持在更年期护理中选择和个性化激素替代疗法。

Consensus-led recommendations supporting choice and personalisation of Hormone replacement therapy in menopause care.

机构信息

Consultant Sexual & Reproductive Health, 4592Liverpool Womens NHS Foundation Trust, Liverpool, UK.

General Practitioner with Extended Role in Menopause and Gynaecology, Woodlands Medical Centre, Oxford, UK.

出版信息

Post Reprod Health. 2022 Jun;28(2):71-78. doi: 10.1177/20533691221084827. Epub 2022 Apr 20.

Abstract

OBJECTIVE

Inequity of access and choice to different hormone replacement therapy (HRT) products across the UK has been suggested (Hillman, 2020). While, the cause is not entirely understood, potential contributors include conflicting national guidance, economic deprivation and a local formulary approach. With a diverse and growing population of women reaching and living well beyond the menopause, the impact of this inequity is becoming more pronounced, and challenges the goal of providing personalised care. The study objective is to establish a consensus that supports a greater equity of access and choice of HRT and provision of individualised care.

STUDY DESIGN

Modified Delphi study designed by UK HCPs with expertise in menopause care. This group identified 40 consensus statements over four key topics, related to access and choice of different HRT products. An online 4-point scale questionnaire, sent to UK HCPs, was used to assess agreement, with a consensus threshold set at 75%.

MAIN OUTCOME MEASURES

150 HCP responses between June and September 2021.

RESULTS

A total of 137 responses were received. Analysis identified 37/40 statements attaining very high agreement (≥ 90%) and 3/40 statements attaining high agreement (< 90% and ≥75%). Nine recommendations were developed with the intent to inform potential improvements to menopause care in the UK.

CONCLUSIONS

The high levels of agreement displayed suggest a desire to change the way menopause care is delivered in the UK. Implementation of the suggested recommendations has the potential to improve equity of access to licensed treatment options, compliant with the NICE recommendation for personalisation of care.

摘要

目的

有人认为,在英国,不同激素替代疗法(HRT)产品的可及性和选择存在不平等现象(Hillman,2020)。虽然其原因尚未完全明了,但潜在的原因包括相互冲突的国家指南、经济贫困和当地处方集方法。随着英国女性人口的多样化和不断增长,达到绝经期并在绝经期后生活得更好的女性越来越多,这种不平等现象的影响变得更加明显,这也对提供个性化护理的目标提出了挑战。本研究的目的是达成共识,支持增加 HRT 的可及性和选择,并提供个性化护理。

研究设计

英国具有更年期护理专业知识的 HCP 参与设计的改良 Delphi 研究。该小组确定了四个关键主题的 40 个共识声明,这些主题与不同 HRT 产品的可及性和选择有关。一项关于 HCP 在线的 4 点量表问卷评估了共识的程度,设定的共识阈值为 75%。

主要结果

2021 年 6 月至 9 月期间,共有 150 名 HCP 做出了回应。分析确定了 37/40 个陈述获得了非常高的一致性(≥90%),3/40 个陈述获得了高一致性(<90%且≥75%)。提出了九条建议,旨在为改善英国更年期护理提供信息。

结论

显示出的高度一致性表明人们希望改变英国更年期护理的方式。实施建议的建议有可能改善获得许可治疗方案的公平性,符合 NICE 关于个性化护理的建议。

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