Bursac Daliborka, Petridis Dimitris, Zaric Bojan, Kovacevic Tomi, Stojsic Vladimir, Sarcev Tatjana, Huang Haidong, Bai Chong, Hohenforst-Schmidt Wolfgang, Kosmidis Christoforos, Sapalidis Konstantinos, Romanidis Konstantinos, Courcoutsakis Nikolaos, Lallas Aimilios, Tsakaldimis Giorgos, Chatzimichael Kyriakoula, Sardeli Chrysanthi, Matthaios Dimitris, Zarogoulidis Paul, Karapantzou Chrysanthi
Faculty of Medicine, University of Novi Sad, Institute for Pulmonary Diseases of Vojvodina, Novi Sad, Serbia.
Department of Food Science and Technology, International Hellenic University, School of Geotechnical Sciences, Aristotle University of Thessaloniki, Greece.
Curr Health Sci J. 2021 Oct-Dec;47(4):507-515. doi: 10.12865/CHSJ.47.04.05. Epub 2021 Dec 31.
The first wave of the COVID-19 pandemic initiated officially in October 2020. Since then several observations have been made regarding the disease and its symptoms.
We included eighty seven in our observational study. Our main aim was to investigate their long term respiratory follow-up in correlation with their initial radiological and laboratory findings and values. The nose swab PCR test for COVID-19 was used for diagnosis. Patients were monitored at 3 and 6 months after their hospital reception whereas basic parameters of health condition (smoking, PO2, SPO2, WBC, CXR, CRP, intercurrent findings, days of nursing, colchicine administration) in joint with gender and age were recorded.
Males seem more susceptible to the viral disease than females in a ratio 1,8:1. The parameters FEV1 and FVC (as % relative changes) were not affected, apart from the DLCO to which CRP (in loge+1 transformation) and SPO2 showed a statistically significant effect.
None of these patients were intubated, or admitted to the intensive care unit. The respiratory function is affected by the virus and the effect is reversed within the first three months. Males are more affected and the radiological and laboratory findings are associated with the respiratory functions.
2020年10月正式开始了第一波新冠疫情。从那时起，人们对该疾病及其症状有了一些观察结果。
我们的观察性研究纳入了87名患者。我们的主要目的是根据他们最初的放射学和实验室检查结果及数值，对他们进行长期的呼吸功能随访调查。采用新冠病毒鼻拭子PCR检测进行诊断。患者在入院后3个月和6个月接受监测，同时记录健康状况的基本参数（吸烟情况、动脉血氧分压、血氧饱和度、白细胞计数、胸部X光、C反应蛋白、并发症状、护理天数、秋水仙碱用药情况）以及性别和年龄。
男性似乎比女性更容易感染这种病毒性疾病，比例为1.8:1。除了一氧化碳弥散量（DLCO）外，第一秒用力呼气容积（FEV1）和用力肺活量（FVC）（以相对变化百分比表示）参数未受影响，对于一氧化碳弥散量，C反应蛋白（以对数+1转换）和血氧饱和度显示出有统计学意义的影响。
这些患者均未接受插管治疗或入住重症监护病房。呼吸功能受到病毒影响，且在头三个月内这种影响会逆转。男性受影响更大，放射学和实验室检查结果与呼吸功能相关。
