Inoue K, Reichelt W
Acta Anaesthesiol Scand. 1986 Oct;30(7):571-3. doi: 10.1111/j.1399-6576.1986.tb02477.x.
Two cases of cardiac asystole and one case of severe bradycardia were seen following a single injection of suxamethonium in a series of 46 adult patients in whom anaesthesia was induced with fentanyl and etomidate. It is suggested that the vagomimetic effects of fentanyl and, possibly also of etomidate, may contribute to the enhancement of the bradycardic effects of suxamethonium.
在46例用芬太尼和依托咪酯诱导麻醉的成年患者中,单次注射琥珀胆碱后出现了2例心搏骤停和1例严重心动过缓。提示芬太尼以及可能还有依托咪酯的拟迷走神经作用,可能促使琥珀胆碱的心动过缓作用增强。