Thomsen H S, Dorph S
Acta Radiol Diagn (Stockh). 1986 Nov-Dec;27(6):705-10. doi: 10.1177/028418518602700615.
Various clinical and laboratory aspects in 15 kidney transplanted patients with urographic evidence of caliceal clubbing and adjacent parenchymal scarring in their native kidneys are reported. These lesions were found in 16 per cent of our series of kidney transplantations; below 35 years of age it was the second most frequent disease. In 9 of these patients severe vesicoureteral reflux had been demonstrated. In the remaining 6 patients reflux nephropathy was only a tentative diagnosis based on a striking similarity in the radiographs and in several clinical findings. Nine patients had symptoms (mainly related to urinary tract infection) from 1 to 17 years before diagnosis/urography, in 5 as early as the first year of life. Recurrent urinary tract infection and renal impairment were the most frequent disorders leading to the diagnosis. Replacement therapy was initiated at an average age of 32.7 years. Following renal transplantation urinary tract infection was documented in 37 per cent of patients whether the patient had been bilaterally nephrectomized or not.
报告了15例肾移植患者的各种临床和实验室情况，这些患者的原生肾存在肾盂杵状变及相邻实质瘢痕形成的尿路造影证据。这些病变在我们的肾移植系列中占16%；在35岁以下患者中，它是第二常见的疾病。其中9例患者已证实存在严重膀胱输尿管反流。其余6例患者的反流性肾病只是基于X线片和一些临床发现的显著相似性做出的初步诊断。9例患者在诊断/尿路造影前1至17年出现症状（主要与尿路感染有关），5例在出生后第一年就出现症状。反复尿路感染和肾功能损害是导致诊断的最常见病症。替代治疗开始的平均年龄为32.7岁。肾移植后，无论患者是否接受双侧肾切除术，37%的患者记录有尿路感染。
