Division of Otolaryngology and Head and Neck Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Division of Otolaryngology and Head and Neck Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy; Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Surg Oncol. 2022 Jun;42:101751. doi: 10.1016/j.suronc.2022.101751. Epub 2022 Apr 6.
Nowadays surgery remains the gold standard of treatment for tongue cancer. Via a more clear and precise terminology, the glossectomy classification by Ansarin et al. facilitates shared communication between surgeons, allowing comparison between published research and improving surgical practice and patient care. To establish the association of glossectomies, according to their classification by Ansarin et al. with overall survival (OS), disease-free survival (DSF), and cause-specific survival (CSS) in tongue cancer, we conducted a systemic retrospective study on 300 consecutive patients affected by primary oral tongue cancer and treated with surgery at the European Institute of Oncology, IRCCS (IEO).
Three hundred patients with tongue squamous cell carcinoma and treated at the Division of Otorhinolaryngology and Head and Neck Surgery of the European Institute of Oncology, IRCCS were cataloged according to the glossectomy classification. OS, DFS, and CSS were compared by surgical treatments.
OS-5yrs was 80% for the type I glossectomy group, 75% for type II, 65% for type III, and 35% for type IV-V. DFS-5yrs was 74%, 60%, 55%, and 27%, respectively for I, II, III, and IV-V glossectomy group; CSS-5yrs was 82%, 80%, 72%, and 48%, respectively for I, II, III, and IV-V glossectomy group (p < 0.01).
This study confirmed that the application of the glossectomy classification was statistically correlated with patients' oncological outcomes.
如今，手术仍然是舌癌的治疗金标准。Ansarin 等人提出的舌切除术分类通过更清晰、更准确的术语，促进了外科医生之间的沟通，使研究结果能够在不同研究之间进行比较，从而提高手术实践和患者护理水平。为了建立 Ansarin 等提出的舌切除术分类与舌癌患者总生存（OS）、无病生存（DFS）和特定原因生存（CSS）之间的关联，我们对 300 例在欧洲肿瘤研究所（IEO）IRCCS 接受手术治疗的原发性口腔舌癌患者进行了系统回顾性研究。
根据欧洲肿瘤研究所（IEO）IRCCS 耳鼻喉头颈外科的舌切除术分类，对 300 例舌鳞状细胞癌患者进行分类。通过手术治疗比较 OS、DFS 和 CSS。
I 型舌切除术组的 OS-5yrs 为 80%，II 型为 75%，III 型为 65%，IV-V 型为 35%。DFS-5yrs 分别为 I、II、III 和 IV-V 型舌切除术组的 74%、60%、55%和 27%；CSS-5yrs 分别为 I、II、III 和 IV-V 型舌切除术组的 82%、80%、72%和 48%（p<0.01）。
本研究证实，舌切除术分类的应用与患者的肿瘤学结果具有统计学相关性。
