Radic Tomislav, Cigic Livia, Glavina Ana, Hrboka Ana, Druzijanic Ana, Musa Leko Ivona, Biocina-Lukenda Dolores
Dental Polyclinic Arena, Zagreb, Remetinecki gaj 2k, 10000 Zagreb, Croatia.
Department of Oral Medicine and Periodontology, School of Medicine, University of Split, Soltanska 2, 21000 Split, Croatia.
Dent J (Basel). 2022 Apr 6;10(4):61. doi: 10.3390/dj10040061.
It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral lichen planus (OLP). The main aim of this study, due to lack of any other study covering this topic, was to investigate lipid profile and assess CVR in patients with OLP.
To create a routine lipid profile, we collected triglyceride serum levels, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol from 63 OLP patients and 63 healthy people representing control subjects. For every patient their individual cardiovascular risk was measured.
In comparison with the tested control subjects, patients with OLP had all parameters of the lipid profile elevated, with no differences of statistical importance. Furthermore, the experimental (OLP) and control groups shared similar mean values of the lipid profile parameters.
The association of OLP with cardiovascular risk was not established and further studies with more subjects involved are required to validate this connection.
据报道，诊断为口腔扁平苔藓的患者血脂异常患病率和心血管疾病风险增加。另一方面，到目前为止，关于口腔扁平苔藓（OLP）患者心血管风险（CVR）这一主题尚无可用数据。由于缺乏涵盖该主题的其他研究，本研究的主要目的是调查OLP患者的血脂谱并评估其CVR。
为建立常规血脂谱，我们收集了63例OLP患者和63名作为对照的健康人的血清甘油三酯水平、总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇。测量了每位患者的个体心血管风险。
与测试对照组相比，OLP患者的血脂谱所有参数均升高，但无统计学差异。此外，实验组（OLP）和对照组的血脂谱参数平均值相似。
未确立OLP与心血管风险之间的关联，需要开展涉及更多受试者的进一步研究来验证这种联系。
