Gkika Despina A, Filiz Volkan, Rangou Sofia, Kyzas George Z, Mitrοpoulos Athanasios C
Department of Chemistry, International Hellenic University, 654 04 Kavala, Greece.
Helmholtz-Zentrum Hereon, Institute of Membrane Research, 21502 Geesthacht, Germany.
Membranes (Basel). 2022 Apr 17;12(4):433. doi: 10.3390/membranes12040433.
Assessing the financial impact of polymers of intrinsic microporosity, otherwise known as PIMs, at the lab scale has been impeded by the absence of a holistic approach that would envelop all related financial parameters, and most importantly any indirect costs, such as laboratory accidents that have been consistently neglected and undervalued in past assessments. To quantify the cost of PIMs in relation to the risks befalling a laboratory, an innovative cost evaluation approach was designed. This approach consists of three stages. Firstly, a two-fold "window of opportunity" (WO) theory is suggested, dividing the total cost profile into two segments, followed up by a qualitative risk analysis to establish the potential cost components. The last stage builds on a total cost of ownership model, incorporating the two types of WO. The total cost of ownership (TCO) approach was selected to ascertain the costs and construct the cost profile of PIMs, according to laboratory experimental data. This model was applied to the synthesis and physicochemical characterization processes. The quantitative analysis revealed that the most influential parameters for synthesis are accidents and energy costs. This is in contrast with the physicochemical characterization process, where the most important determinant is the energy cost.
在实验室规模下评估固有微孔聚合物（即PIMs）的财务影响，一直受到缺乏一种能涵盖所有相关财务参数，尤其是任何间接成本（如实验室事故，在过去的评估中一直被忽视和低估）的整体方法的阻碍。为了量化PIMs的成本与实验室面临的风险之间的关系，设计了一种创新的成本评估方法。该方法包括三个阶段。首先，提出了一种双重“机会窗口”（WO）理论，将总成本概况分为两个部分，随后进行定性风险分析以确定潜在的成本组成部分。最后一个阶段基于总拥有成本模型，纳入了两种类型的WO。根据实验室实验数据，选择总拥有成本（TCO）方法来确定成本并构建PIMs的成本概况。该模型应用于合成和物理化学表征过程。定量分析表明，合成过程中最具影响力的参数是事故和能源成本。这与物理化学表征过程形成对比，在该过程中最重要的决定因素是能源成本。
