Bruet Vincent, Mosca Marion, Briand Amaury, Bourdeau Patrick, Pin Didier, Cochet-Faivre Noëlle, Cadiergues Marie-Christine
Veterinary Dermatology Referral Services, 44100 Nantes, France.
Université de Lyon, VetAgro Sup, Interactions Cells Environment, UPSP 2016.A104, 69280 Marcy l'Etoile, France.
Vet Sci. 2022 Mar 22;9(4):149. doi: 10.3390/vetsci9040149.
Pruritus is a common clinical sign in many skin disorders and is currently the main complaint in canine dermatology. Pruritic skin diseases can affect the quality of life of dogs and their owners. Several families of antipruritic drugs are available to help control pruritus in dogs. The aim of this review is to help practitioners select the most appropriate symptomatic treatment in the most frequent situations of dermatological pruritus in dogs. The molecules reviewed here are systemic and topical glucocorticoids, antihistamines, ciclosporin, oclacitinib and lokivetmab. A level of evidence (1, 2 or 3) has been established according to a detailed algorithm for each individual study in the literature published between 1990 and March 2021. The guidelines result from evidence grading using the strength of recommendation taxonomy (SoRT) and clinical recommendations using a thorough methodology.
瘙痒是许多皮肤疾病常见的临床症状，目前是犬类皮肤病学的主要诉求。瘙痒性皮肤病会影响犬只及其主人的生活质量。有几类止痒药物可用于帮助控制犬只的瘙痒。本综述的目的是帮助从业者在犬类皮肤瘙痒最常见的情况下选择最合适的对症治疗方法。这里所综述的药物分子包括全身性和局部用糖皮质激素、抗组胺药、环孢素、奥克拉替尼和洛维单抗。根据1990年至2021年3月发表的文献中每项单独研究的详细算法确定了证据水平（1、2或3）。这些指南是通过使用推荐强度分类法（SoRT）进行证据分级以及采用全面方法进行临床推荐而得出的。
