Barsoum I S, Mostafa M S, Shihab A A, el Alamy M, Habib M A, Colley D G
Am J Trop Med Hyg. 1987 Jan;36(1):97-101. doi: 10.4269/ajtmh.1987.36.97.
The prevalence of trachoma in school children and ophthalmological patients in rural villages of the Qalyub Governorate of Egypt was determined by clinical and laboratory diagnostic procedures and reported as mild, moderate, or severe according to the WHO classification scheme. Of 777 primary school students examined in 3 villages, 204 (26%) had clinically active trachoma. The overall prevalence of the disease in this population ranged from 16% to 35%. The prevalence of infection was higher in younger groups and decreased throughout primary school. Of 312 patients with ocular complaints examined at the village outpatient clinics, 100 (32%) had trachoma infections. Monoclonal FA staining showed higher sensitivity in detecting positive cases of trachoma than did Giemsa staining. This study has shown that trachoma is still prevalent in rural Egypt and that the monoclonal FA staining is a relatively sensitive and practical test for the laboratory diagnosis of trachoma in a field study, where reasonable facilities for culture diagnosis are not available.
通过临床和实验室诊断程序确定了埃及盖勒尤卜省农村地区学童和眼科患者沙眼的患病率,并根据世界卫生组织的分类方案报告为轻度、中度或重度。在3个村庄接受检查的777名小学生中,204名(26%)患有临床活动性沙眼。该人群中该疾病的总体患病率在16%至35%之间。感染率在较年轻组中较高,并在整个小学阶段下降。在村庄门诊接受检查的312名眼部不适患者中,100名(32%)患有沙眼感染。单克隆荧光抗体染色在检测沙眼阳性病例方面比吉姆萨染色具有更高的敏感性。这项研究表明,沙眼在埃及农村地区仍然普遍存在,并且在现场研究中,当没有合理的培养诊断设施时,单克隆荧光抗体染色是一种相对敏感且实用的沙眼实验室诊断检测方法。