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欧洲、日本和中国血统正常男性对酒精的急性心血管反应的异同:单变量和多变量分析

Similarities and differences in acute cardiovascular responses to alcohol among normal men of European, Japanese, and Chinese ancestry: a univariate and multivariate analysis.

作者信息

Reed T E, Hanna J M

出版信息

Alcohol Clin Exp Res. 1986 Dec;10(6):560-3. doi: 10.1111/j.1530-0277.1986.tb05144.x.

DOI:10.1111/j.1530-0277.1986.tb05144.x
PMID:3544905
Abstract

Normal young adult males residing in Hawaii (46 of European ancestry, 30 Japanese, 27 Chinese) were tested for changes in heart rate and blood pressure following a dose of 0.59 g of ethanol/kg. The two Oriental groups did not differ in mean changes but, when pooled, differed from Europeans, having increased heart rate and decreased blood pressure. Within-race analyses showed that, contrary to the literature, all three groups have great interindividual differences in cardiovascular responses. In addition, the three races show a basically similar multivariate response: blood pressure more variable than heart rate and blood pressure changes uncorrelated with heart rate changes.

摘要

对居住在夏威夷的正常年轻成年男性(46名欧洲血统、30名日本人、27名中国人)进行了测试,以观察在服用0.59克乙醇/千克剂量后心率和血压的变化。两个东方人群组在平均变化方面没有差异,但合并后与欧洲人不同,他们的心率增加且血压降低。种族内分析表明,与文献相反,所有三个组在心血管反应方面都存在很大的个体差异。此外,这三个种族显示出基本相似的多变量反应:血压比心率更具变异性,且血压变化与心率变化不相关。

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引用本文的文献

1
Between- and within-race variation in acute cardiovascular responses to alcohol: evidence for genetic determination in normal males in three races.
Behav Genet. 1986 Nov;16(6):585-98. doi: 10.1007/BF01066285.