Department of Neurosurgery, Faculty of Medicine, Lucian Blaga University, Sibiu, Romania.
Department of Neurosurgery, County Emergency Hospital, Sibiu, Romania.
J Med Life. 2022 Mar;15(3):319-327. doi: 10.25122/jml-2020-0151.
In December 2019, in Wuhan, China, the first cases of infection with SARS-CoV 2 responsible for COVID-19 disease were identified. SARS-CoV 2 was declared a pandemic on March 11, 2020, and since then has attracted the medical world's attention. The threat to humans' health that this emerging pandemic could leave raises awareness on the importance of understanding the mechanisms that underlie the developing conditions. The epidemiology, clinical picture, and pathogenesis of COVID-19 show that this virus presents new strategies to overcome the past defensive medicine. While all the current data has focused on the pulmonary and cardiovascular manifestations, little has been written about the neurological implications of the disease. This review updates new clinical aspects that SARS-CoV 2 expresses in humans by focusing primarily on neurological manifestations. The damage to the nervous system became more apparent - anosmia, ageusia, polyneuritis, meningitis, meningoencephalitis, stroke, acute necrotizing encephalopathy. Oxygen therapy is vital for those in critical health situations. Finally, prevention is the most important element in breaking the epidemiological chain.
2019 年 12 月，在中国武汉，首次发现了导致 COVID-19 疾病的 SARS-CoV-2 感染病例。SARS-CoV-2 于 2020 年 3 月 11 日被宣布为大流行，此后引起了医学界的关注。这种新出现的大流行可能对人类健康造成的威胁引起了人们对了解发病机制重要性的认识。COVID-19 的流行病学、临床表现和发病机制表明，这种病毒提出了克服过去防御医学的新策略。虽然所有当前的数据都集中在肺部和心血管表现上，但关于该疾病的神经学影响却很少被提及。这篇综述通过主要关注神经系统表现，更新了 SARS-CoV-2 在人类中表达的新的临床方面。神经系统损伤变得更加明显——嗅觉丧失、味觉丧失、多发性神经炎、脑膜炎、脑膜脑炎、中风、急性坏死性脑病。对于处于危急健康状况的患者，氧疗至关重要。最后，预防是打破流行病学链条的最重要因素。
