氩等离子体凝固术在儿童胃肠道血管发育异常中的应用——来自三级医疗中心的经验
Application of Argon Plasma Coagulation for Gastrointestinal Angiodysplasia in Children- Experience From a Tertiary Center.
作者信息
Yeh Pai-Jui, Le Puo-Hsien, Chen Chien-Chang, Chao Hsun-Chin, Lai Ming-Wei
机构信息
Linkou Branch, Department of Pediatric Gastroenterology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Linkou Branch, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
出版信息
Front Pediatr. 2022 Apr 5;10:867632. doi: 10.3389/fped.2022.867632. eCollection 2022.
BACKGROUND
Argon plasma coagulation (APC) has been applied in adults to treat various diseases, including vascular lesions in the gastrointestinal (GI) tract. However, angiodysplasia (AD) is an uncommon cause of pediatric GI bleeding, while the experience of treating AD with APC was rarely reported.
METHODS
Five children with AD in the GI tract successfully treated with APC were reviewed.
RESULTS
Three of the five patients were girls, and the age at diagnosis ranged from 1.5 months to 10.5 years of age. One patient with gastric AD manifested with tarry stool, and the rest had colonic AD, which caused various degrees of bloody stool. Three patients had evident anemia. All patients received an endoscopic diagnosis, and two had compatible findings in radiographic exams. Each patient underwent one APC treatment session, and none encountered procedure-related complications or re-bleeding.
CONCLUSION
AD can be an etiology of GI bleeding even in neonates. APC is an effective and safe therapy for symptomatic AD in children.
背景
氩离子凝固术（APC）已应用于成人治疗各种疾病，包括胃肠道（GI）血管病变。然而，血管发育异常（AD）是儿童胃肠道出血的罕见原因，而用APC治疗AD的经验鲜有报道。
方法
回顾了5例经APC成功治疗的胃肠道AD患儿。
结果
5例患者中3例为女孩，诊断时年龄为1.5个月至10.5岁。1例胃AD患者表现为柏油样便，其余为结肠AD，导致不同程度的便血。3例患者有明显贫血。所有患者均接受内镜诊断，2例在影像学检查中有相符表现。每位患者均接受1次APC治疗，无一例出现与手术相关的并发症或再次出血。
结论
即使在新生儿中，AD也可能是胃肠道出血的病因。APC是治疗儿童有症状AD的一种有效且安全的疗法。
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