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特发性葡萄膜渗漏综合征的临床特征与手术治疗

Clinical characteristics and surgical treatment of idiopathic uveal effusion syndrome.

作者信息

Shen Zhi-Jun, Shen Lin, Wang Hong

机构信息

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Science Key Lab, Beijing 100730, China.

出版信息

Int J Ophthalmol. 2022 Apr 18;15(4):604-608. doi: 10.18240/ijo.2022.04.13. eCollection 2022.

Abstract

AIM

To investigate the clinical characteristics of idiopathic uveal effusion syndrome (IUES) and to identify effective surgical modalities for its treatment.

METHODS

This retrospective analysis included clinical data of 33 eyes from 26 patients with IUES at Beijing Tongren Hospital. Records of eye examinations, ocular ultrasound, ocular ultrasound biomicroscopy (UBM), and follow-up surgical treatment were reviewed and analyzed.

RESULTS

Of 26 patients, 17 (65.4%) were male and 9 (34.6%) were female. The average age of disease onset was 46.8y (range: 22-64y). Seven patients (26.9%) showed retinal detachment in both eyes at presentation. B-ultrasound showed the presence of retinal detachment in one eye or both eyes. All patients had binocular ciliary leakage and detachment. Eyes with retinal detachment underwent four-quadrantic partial-thickness sclerectomy and sclerostomy. Subretinal fluid resolution was achieved within 6mo. Recurrence was observed in three eyes and was resolved with re-operation.

CONCLUSION

Ophthalmic ultrasound and UBM, among others, can be helpful in the diagnosis of IUES. Sclerectomy and sclerostomy are surgical modalities that can successfully treat the disease. Some patients may experience recurrence after surgery; reoperation remains safe and effective for them. Long-term follow-up is essential in such settings.

摘要

目的

探讨特发性葡萄膜渗漏综合征(IUES)的临床特征,并确定有效的手术治疗方式。

方法

本回顾性分析纳入了北京同仁医院26例IUES患者的33只眼的临床资料。对眼部检查、眼部超声、眼部超声生物显微镜检查(UBM)及后续手术治疗记录进行回顾分析。

结果

26例患者中,男性17例(65.4%),女性9例(34.6%)。平均发病年龄为46.8岁(范围:22 - 64岁)。7例患者(26.9%)初诊时双眼出现视网膜脱离。B超显示单眼或双眼存在视网膜脱离。所有患者均有双眼睫状体渗漏和脱离。发生视网膜脱离的眼行四象限部分厚度巩膜切除术和巩膜造瘘术。视网膜下液在6个月内消退。3只眼出现复发,再次手术治愈。

结论

眼部超声和UBM等检查有助于IUES的诊断。巩膜切除术和巩膜造瘘术是能够成功治疗该病的手术方式。部分患者术后可能复发;再次手术对他们仍然安全有效。在此类情况下,长期随访至关重要。

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