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蕈样肉芽肿与放射治疗。联合治疗的价值:全身电子线治疗和全身光子治疗

[Mycosis fungoides and radiotherapy. Value of the combination: total skin electron therapy and whole-body photon therapy].

作者信息

Lambert D, Bousser A M, Dalac S, Godard W, Lepinoy D, Horiot J C

出版信息

Ann Dermatol Venereol. 1986;113(6-7):541-7.

PMID:3545028
Abstract

Between 1975 and 1983, 46 patients with mycosis fungoides (MF) were treated with radiotherapy. The patients were classified according to the Stanford system (table II) and to the TNMB system (table III). The superficial lesions were treated with total skin electron-therapy (TSE) (7), and the visceral and lymph node lesions received additional whole-body photon therapy (WBP) (7). The results are summarized in table I. Initial complete regression was obtained in 21 of the 46 patients; 15 had partial regression. At the moment, 11 are alive without any apparent lesion. There were 9 complete remissions in each of the stage I and stage II groups. In stages III and IVa groups the course of the disease was improved by the two types of irradiation combined. In stage IVb patients the leukaemia was not improved. The survival curves (fig. 1 to 6) offer a simplified representation of the factors responsible for a favourable course.

摘要

1975年至1983年间,46例蕈样肉芽肿(MF)患者接受了放射治疗。患者根据斯坦福系统(表二)和TNMB系统(表三)进行分类。浅表病变采用全身电子线治疗(TSE)(7例),内脏和淋巴结病变则额外接受全身光子治疗(WBP)(7例)。结果总结于表一。46例患者中有21例获得初始完全缓解;15例部分缓解。目前,11例患者存活且无明显病变。I期和II期组各有9例完全缓解。在III期和IVa期组,两种放疗联合可改善疾病进程。在IVb期患者中,白血病未得到改善。生存曲线(图1至6)以简化形式呈现了促成良好病程的因素。

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