肺炎克雷伯菌中黏菌素耐药性与广谱受体缺陷之间的关联。
Association between colistin resistance and broad-spectrum recipient deficiency in Klebsiella pneumoniae.
作者信息
Lamousin-White M, O'Callaghan R J
出版信息
Antimicrob Agents Chemother. 1986 Dec;30(6):964-5. doi: 10.1128/AAC.30.6.964.
Abstract
A colistin-resistant mutant of Klebsiella pneumoniae served well as a donor but not as a recipient in conjugation. A nearly 1,000-fold difference between colistin-susceptible and colistin-resistant forms of this strain was observed by using donors of plasmids of four incompatibility groups. Recipient efficiency was not restored by filter matings.
摘要
肺炎克雷伯菌的耐黏菌素突变体在接合中作为供体表现良好，但作为受体则不然。通过使用四个不相容群质粒的供体，观察到该菌株的黏菌素敏感型和耐黏菌素型之间存在近1000倍的差异。滤膜交配并未恢复受体效率。
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