Christou T, Subramanian S, Fung C
Arch Intern Med. 1987 Feb;147(2):377-8.
We diagnosed lymphoma 14 months after the patient presented with paroxysmal nocturnal hemoglobinuria. To our knowledge, this is the first presentation of both conditions in a patient. One possible explanation is that both conditions could be traced to an alteration in the most primitive hemic stem cell. Such an alteration would have resulted in abnormalities of both lymphoid and nonlymphoid cell lines.
在该患者出现阵发性夜间血红蛋白尿14个月后，我们诊断其患有淋巴瘤。据我们所知，这是首例患者同时出现这两种病症。一种可能的解释是，这两种病症都可追溯到最原始的造血干细胞发生了改变。这样的改变会导致淋巴细胞系和非淋巴细胞系均出现异常。
