COVID-19 大流行期间的器官移植 - 对南非西开普省已故器官捐献者推荐和同意率的影响。

Organ transplantation during the COVID-19 pandemic - impact on deceased organ donor referrals and consent rates in the Western Cape, South Africa.

机构信息

Department of Surgery, Faculty of Health Sciences, Groote Schuur Hospital, University of Cape Town, South Africa.

出版信息

S Afr J Surg. 2022 Mar;60(1):55-58.

Abstract

BACKGROUND

The impact of the COVID-19 pandemic on transplantation is multifactorial. This study reports on its influence on deceased donation for transplantation in the Western Cape.

METHODS

The volume of referrals and those who were consented for organ donation in the province in the pre-pandemic period of May 2017 to February 2020 were compared to those of the initial pandemic period (March through December 2020).

RESULTS

Prior to the pandemic, there were 201 deceased donor referrals in the Western Cape province - 152 (75.6%) and 49 (24.4%) in public and private sectors, respectively. The mean referral rates ranged between 59-69 referrals per year, translating into a monthly rate of 4.8 (range 2.8-5.8). During the first 10 months of the pandemic, there were 18 referrals - 12 (66.7%) and six (33.3%) in the public and private sectors; a decrease of 63%, with a mean monthly referral rate of 1.8. The overall consent rate prior to the pandemic in the public and private sectors was 36.6% (38% and 27%, respectively) with an increase to 44.4% (37.5% and 62.5%) during the pandemic.

CONCLUSION

Despite a 10% increase in consent rate for deceased donation during the COVID-19 pandemic, there was a significant decrease in the number of potential donors referred. Strategies to improve organ donation and transplantation during and after the COVID-19 pandemic are required.

摘要

背景

COVID-19 大流行对移植的影响是多方面的。本研究报告了其对西开普省器官捐献的影响。

方法

将 2017 年 5 月至 2020 年 2 月大流行前该省的转介量和同意进行器官捐献者数量与大流行初期（2020 年 3 月至 12 月）进行比较。

结果

大流行前，西开普省有 201 名已故供体转介者，公共部门有 152 名（75.6%），私营部门有 49 名（24.4%）。转介率平均在 59-69 例/年之间，换算成每月 4.8 例（范围为 2.8-5.8 例）。在大流行的前 10 个月，有 18 例转介，公共部门有 12 例（66.7%），私营部门有 6 例（33.3%），减少了 63%，每月平均转介率为 1.8 例。大流行前，公共和私营部门的总体同意率分别为 36.6%（38%和 27%）和 44.4%（37.5%和 62.5%），有所增加。