Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Medicine (Baltimore). 2022 Mar 11;101(10):e29032. doi: 10.1097/MD.0000000000029032.
The incidence of diabetic peripheral neuropathy (DPN) is increasing year by year. If patients cannot receive timely and effective treatment, DPN may lead to diabetic foot ulcers or even amputation. This risk factor has been widely concerned around the world. Massage, as a non-invasive physical therapy method, is gradually being applied in the adjuvant treatment of DPN. However, there is no systematic review of the adjuvant treatment of DPN by massage. Our study will explore the effectiveness and safety of massage applied in DPN.
Eight electronic databases (PubMed, Cochrane, Web of Science, Sinomed, Embase, China National Knowledge Infrastructure, WanFang Data, Chongqing VIP Information) will be searched by our computer on February 9, 2022. A randomized controlled trial (RCT) of adjuvant massage therapy for DPN was screened. Primary outcome measures: efficiency, nerve conduction velocity. Secondary outcome measures: pain, blood glucose, and incidence of adverse reactions. The quality of the study was evaluated by two researchers using the RCT bias risk assessment tool in the Cochrane review manual Handbook5.4, and meta-analysis was performed by RevMan5.4 software.
RCTs will be used to evaluate the clinical efficacy of massage adjuvant therapy in DPN.
This study will provide evidence-based evidence for the safety and effectiveness of massage adjuvant therapy in DPN.
INPLASY202220025.
糖尿病周围神经病变（DPN）的发病率逐年上升。如果患者不能得到及时有效的治疗，DPN 可能导致糖尿病足溃疡，甚至截肢。这一风险因素已引起全球广泛关注。按摩作为一种非侵入性的物理治疗方法，正逐渐应用于 DPN 的辅助治疗中。然而，目前尚缺乏按摩辅助治疗 DPN 的系统评价。我们的研究将探讨按摩在 DPN 中的应用的有效性和安全性。
我们将于 2022 年 2 月 9 日通过计算机在 8 个电子数据库（PubMed、Cochrane、Web of Science、Sinomed、Embase、中国国家知识基础设施、万方数据、重庆维普信息）中搜索辅助按摩治疗 DPN 的随机对照试验（RCT）。主要结局指标：效率、神经传导速度。次要结局指标：疼痛、血糖和不良反应发生率。使用 Cochrane 综述手册 5.4 中的 RCT 偏倚风险评估工具，由两名研究者评估研究质量，并使用 RevMan5.4 软件进行荟萃分析。
将使用 RCT 评估按摩辅助治疗 DPN 的临床疗效。
本研究将为按摩辅助治疗 DPN 的安全性和有效性提供循证医学证据。
INPLASY202220025。
