Department of Pediatrics of Korean Medicine, Korean Medicine Hospital, Dongguk University Bundang Medical Center, Republic of Korea.
Department of Pediatrics of Korean Medicine, Graduate School of Dongguk University, Republic of Korea.
Medicine (Baltimore). 2022 Mar 11;101(10):e29035. doi: 10.1097/MD.0000000000029035.
This study is the protocol to evaluate the clinical evidence for external treatments using herbal medicine (ETHM) with tuina as a congenital muscular treatment (CMT) in pediatrics.
Eleven databases will be searched until June 2022, without any language restrictions: four English databases (MEDLINE, Pubmed, EMBASE, and The Cochrane Central Register of Database of Controlled Trials), three Chinese databases (China National Knowledge Infrastructure, Chinese Scientific Journal Database, and Wan Fang Database), and four Korean electronic databases (Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, National Digital Science Links, and Research Information Sharing Service). This review will include randomized clinical trials (RCTs) of ETHM with tuina as an intervention versus the same tuina. All published RCTs for any ETHM for CMT will be included. Non-RCTs, RCT protocol, animal studies, case reports, reviews, and surveys will be excluded. The methodological quality assessment will be performed using the Cochrane risk of bias (ROBs). Review Manager version 5.4. will be used for the data synthesis and quantitative analysis.
The systematic review and meta-analysis will provide evidence for ETHM as a treatment of CMT. The evidence can help clinicians and patients recognize more effective therapeutic and safe inventions.
INPLASY202210017.
本研究旨在评估将草药（ETHM）与推拿结合作为小儿先天性肌营养不良（CMT）的外部治疗的临床证据。
本研究将检索 11 个数据库，检索时间截至 2022 年 6 月，不限制语言：4 个英文数据库（MEDLINE、PubMed、EMBASE 和 The Cochrane Central Register of Database of Controlled Trials），3 个中文数据库（中国知网、中文科技期刊数据库和万方数据库）和 4 个韩国电子数据库（Oriental Medicine Advanced Searching Integrated System、Korean Studies Information Service System、National Digital Science Links 和 Research Information Sharing Service）。本综述将包括以 ETHM 与推拿作为干预措施与相同推拿的随机对照试验（RCTs）。所有发表的关于任何用于 CMT 的 ETHM 的 RCT 都将被纳入。非 RCT、RCT 方案、动物研究、病例报告、综述和调查将被排除在外。使用 Cochrane 偏倚风险（ROB）评估方法进行方法学质量评估。使用 Review Manager 版本 5.4 进行数据合成和定量分析。
系统评价和荟萃分析将为 ETHM 作为 CMT 治疗方法提供证据。该证据可以帮助临床医生和患者认识到更有效的治疗和安全的发明。
INPLASY 注册号：INPLASY202210017。
