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基于智能手机的眼震诊断:用于眩晕靶向检测的创新应用程序的开发。

Smartphone-based nystagmus diagnostics: development of an innovative app for the targeted detection of vertigo.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, "Otto Körner", Rostock University Medical Center, Doberaner Strasse 137-139, 18057, Rostock, Germany.

Faculty of Computer Science and Electrical Engineering, Institute of Automation, University Rostock, Albert-Einstein-Strasse 22, 18059, Rostock, Germany.

出版信息

Eur Arch Otorhinolaryngol. 2022 Dec;279(12):5565-5571. doi: 10.1007/s00405-022-07385-9. Epub 2022 Apr 22.

Abstract

BACKGROUND

In medicine, the symptom of dizziness is one of the most common multidisciplinary causes of emergency medical presentation. Attending physicians are often faced with difficult decisions when evaluating patients with dizziness. A rapid differential diagnostic decision must be made during the initial examination. The goal of this study, was to develop a smartphone-based app that can diagnose and qualify nystagmus. The app should enable differentiation between acute emergencies such as strokes ("central vertigo") and vestibular disorders ("peripheral vertigo") using and recognizing or analyzing the accompanying symptom "nystagmus".

MATERIALS AND METHODS

This prospective study was conducted at the Department of Otolaryngology, Head and Neck Surgery "Otto Körner", Rostock (Germany). The experimental study design consisted of two test runs and two control runs. In the two test runs, nystagmus was tracked and evaluated by caloric and optokinetic stimulation, respectively, through a custom-developed app. Sensitivity and correlation were calculated for the app's application performance and compared under different experimental conditions.

RESULTS

The patient sample included twenty healthy participants with a mean age of 25.6 years (± 2.2 SD) who participated in the study. The overall sensitivity of detection of nystagmus averaged 82.14% in the optokinetic stimulation test trials. There is no correlation regarding specific subject data and sensitivity.

CONCLUSIONS

The results of our experimental validation study show that a smartphone-based nystagmus app is a useful tool for vertigo diagnosis. The results of our analyses show that it is possible to diagnose nystagmus and determine shape or direction with the app.

摘要

背景

在医学中,头晕症状是导致急诊的最常见的多学科原因之一。医生在评估头晕患者时,经常需要做出艰难的决策。在初步检查期间,必须迅速做出鉴别诊断决策。本研究的目的是开发一种基于智能手机的应用程序,用于诊断和确定眼球震颤。该应用程序应能够通过识别或分析伴随症状“眼球震颤”,区分急性紧急情况,如中风(“中枢性眩晕”)和前庭障碍(“周围性眩晕”)。

材料和方法

这项前瞻性研究在罗斯托克(德国)耳鼻咽喉头颈外科“奥托·科纳”(Department of Otolaryngology, Head and Neck Surgery "Otto Körner")进行。实验研究设计包括两个测试运行和两个对照运行。在两个测试运行中,通过定制开发的应用程序分别通过冷热水试验和视动性试验跟踪和评估眼球震颤。计算了应用程序的应用性能的灵敏度和相关性,并在不同的实验条件下进行了比较。

结果

该患者样本包括 20 名平均年龄为 25.6 岁(±2.2 标准差)的健康参与者,他们参加了这项研究。在视动性刺激试验中,眼球震颤的总体检测灵敏度平均为 82.14%。特定的主题数据和灵敏度之间没有相关性。

结论

我们的实验验证研究结果表明,基于智能手机的眼球震颤应用程序是一种用于眩晕诊断的有用工具。我们的分析结果表明,使用该应用程序可以诊断眼球震颤并确定其形状或方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a26/9649472/55b1d5d6ffbc/405_2022_7385_Fig1_HTML.jpg

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