Shaoyang Central Hospital, Shaoyang.
Hunan Children's Hospital, Hunan.
Neurologist. 2023 Jan 1;28(1):42-45. doi: 10.1097/NRL.0000000000000428.
Moyamoya syndrome is commonly associated with sickle cell anemia, neurofibromatosis type 1, cranial therapeutic irradiation, and Down syndrome. However, it is rare for Moyamoya syndrome associated with Graves' disease.
Here we report a case of Moyamoya syndrome associated with Graves' disease in a 19-year-old girl with sudden weakness of the right arm, progressive caries, and alopecia for 4 years. Brain magnetic resonance imaging revealed acute intraventricular hemorrhage and cerebral infarction of left middle cerebral artery territory and narrowing of the proximal portion of bilateral anterior and middle cerebral arteries.
Acute cerebral infarction and intraventricular hemorrhage can occur simultaneously in Moyamoya syndrome associated with Graves' disease. Hydrocortisone, combined with prothiouracil medication, can correct thyroid dysfunction and improve neurological function. Caries may be the first symptom of Graves' disease.
烟雾病通常与镰状细胞贫血、神经纤维瘤病 1 型、颅部放疗和唐氏综合征相关。然而，与格雷夫斯病相关的烟雾病则较为罕见。
我们在此报告一例 19 岁女性患者，因右侧手臂突然无力、渐进性龋齿和脱发 4 年就诊，诊断为格雷夫斯病合并烟雾病。颅脑磁共振成像显示左侧大脑中动脉区域急性脑室出血和脑梗死，双侧大脑前动脉和大脑中动脉近端狭窄。
格雷夫斯病合并烟雾病可同时发生急性脑梗死和脑室出血。氢化可的松联合丙硫氧嘧啶治疗可纠正甲状腺功能障碍，改善神经功能。龋齿可能是格雷夫斯病的首发症状。
