简讯：细胞器降解
SnapShot: Organelle degradation.
作者信息
Mizushima Noboru
机构信息
Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
出版信息
Mol Cell. 2022 Apr 21;82(8):1604-1604.e1. doi: 10.1016/j.molcel.2022.03.015.
Organelles are continuously turned over as part of cellular homeostasis and adaptation. Most organelles, even including the nucleus, are degraded by lysosomes via different pathways, such as macroautophagy, microautophagy, organelle-derived vesicle degradation, and crinophagy. In some specific cases-for example, in lens fiber cells-organelles are degraded by cytosolic phospholipases. To view this SnapShot, open or download the PDF.
作为细胞稳态和适应性的一部分，细胞器不断更新。大多数细胞器，甚至包括细胞核，都通过不同途径被溶酶体降解，如巨自噬、微自噬、细胞器衍生囊泡降解和分泌自噬。在某些特定情况下，例如在晶状体纤维细胞中，细胞器由胞质磷脂酶降解。要查看此快照，请打开或下载PDF。
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