English G M, Spector S, Farr R, Carr R
Arch Otolaryngol Head Neck Surg. 1987 Apr;113(4):377-9. doi: 10.1001/archotol.1987.01860040039013.
Nearly 700 specimens of polyps and sinus tissues from 12 patients with asthma and aspirin idiosyncrasy were studied with histochemical and immunofluorescent immunoglobulin techniques. Hematoxylin-eosin, Giemsa, and Wright's stains were used for the histochemical analyses. Immunofluorescent antibodies for IgG, IgA, IgM, IgE, IgD, anti-C3, albumin, and fibrin were used. There was a uniform inflammatory reaction in all the tissues. A thick basement membrane and epithelial changes were also present. Immunofluorescent immunoglobulins were consistent in quantity and location in these tissues. IgG, IgA, and IgM were associated with inflammation. IgE was present in all the specimens, but this does not necessarily indicate a reagin-mediated reaction. Anti-C3 excluded the possibility of a hereditary absence of C1 esterase inhibitor.
对12例哮喘和阿司匹林特异反应患者的近700份息肉和鼻窦组织标本采用组织化学和免疫荧光免疫球蛋白技术进行了研究。苏木精-伊红染色、吉姆萨染色和瑞氏染色用于组织化学分析。使用了针对IgG、IgA、IgM、IgE、IgD、抗C3、白蛋白和纤维蛋白的免疫荧光抗体。所有组织均有一致的炎症反应。还存在厚基底膜和上皮变化。这些组织中免疫荧光免疫球蛋白在数量和位置上是一致的。IgG、IgA和IgM与炎症相关。所有标本中均存在IgE，但这不一定表明是反应素介导的反应。抗C3排除了遗传性缺乏C1酯酶抑制剂的可能性。
