Department of Infection Control and Prevention, Faculty of Nursing, Toho University, Tokyo, Japan.
Department of Infection Control and Prevention, Faculty of Nursing, Toho University, Tokyo, Japan.
J Hosp Infect. 2022 Aug;126:16-20. doi: 10.1016/j.jhin.2022.04.004. Epub 2022 Apr 19.
The efficacy of bipolar ionization in the healthcare setting has yet to be proven. A major limitation of studies sponsored by industry has been the assessment of efficiency within test chambers in which ozone levels are not adequately controlled.
To assess the effectiveness of bipolar ionization against antimicrobial-resistant bacteria, fungi and human coronavirus within a controlled test chamber designed to mitigate the effect of ozone.
Bacteria- and fungi-inoculated gauze pads, and human coronavirus 229E-inoculated stainless steel plates were placed within the vicinity of the AIO-2 bipolar ionizer and left at room temperature (2 h for coronavirus and 4 h for bacteria and fungi).
Four hours of exposure to bipolar ionization showed a 1.23-4.76 log reduction, corresponding to a 94.2->99.9% colony-forming units/gauze reduction, in Clostridioides difficile, Klebsiella pneumoniae carbapenemase-producing K. pneumoniae, meticillin-resistant Staphylococcus aureus and multi-drug-resistant S. aureus. A 1.2 log 50% tissue culture infectious dose reduction in human coronavirus was observed after 2 h.
The assessment of bipolar ionization systems merits further investigation as an infection control measure.
在医疗环境中，双极电离的疗效尚未得到证实。由行业赞助的研究的一个主要局限性是在臭氧水平未得到充分控制的测试室内评估效率。
在设计用于减轻臭氧影响的受控测试室内评估双极电离对抗微生物耐药细菌、真菌和人类冠状病毒的效果。
将细菌和真菌接种的纱布垫和接种了人类冠状病毒 229E 的不锈钢板放在 AIO-2 双极离子发生器附近，并在室温下放置（冠状病毒 2 小时，细菌和真菌 4 小时）。
暴露于双极电离 4 小时可使艰难梭菌、产碳青霉烯酶的肺炎克雷伯菌、耐甲氧西林金黄色葡萄球菌和多药耐药金黄色葡萄球菌的菌落形成单位/纱布减少 1.23-4.76 对数，相当于减少 94.2->99.9%。暴露于双极电离 2 小时后，观察到对人类冠状病毒的 50%组织培养感染剂量减少 1.2 对数。
作为感染控制措施，评估双极电离系统值得进一步研究。
