西酞普兰与阿米替林抗抑郁作用的比较。
A comparison of the antidepressant action of citalopram and amitriptyline.
作者信息
Shaw D M, Thomas D R, Briscoe M H, Watkins S E, Crimmins R, Harris B, Lovett J, Raj M, Lloyd A T, Osborne C
出版信息
Br J Psychiatry. 1986 Oct;149:515-7. doi: 10.1192/bjp.149.4.515.
PMID:3545354
Abstract
The response of patients with major depressive illness to citalopram of amitriptyline was compared in a double-blind multi-centre trial. No differences in efficacy were observed, but citalopram had less hypnotic effect, and a remarkably lower profile of side-effects.
摘要
在一项双盲多中心试验中，比较了重度抑郁症患者对西酞普兰和阿米替林的反应。未观察到疗效上的差异，但西酞普兰的催眠作用较小，且副作用明显较少。
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