新型抗抑郁化合物西酞普兰的开放性初步研究
[Open preliminary study of new antidepressive compound: citalopram].
作者信息
Ropert R, Lôo H, Gay C
出版信息
Encephale. 1984;10(3):131-4.
PMID:6594229
Abstract
The antidepressant effect of citalopram, a specific inhibitor of the reuptake of serotonin, was explored in an open phase II study involving twenty-one patients hospitalized for depression. Fourteen patients responded, six did not and one was excluded from the study. These preliminary results suggest that citalopram is an effective, well tolerated antidepressant.
摘要
在一项开放性II期研究中，对21名因抑郁症住院的患者探讨了选择性5-羟色胺再摄取抑制剂西酞普兰的抗抑郁作用。14名患者有反应，6名无反应，1名被排除在研究之外。这些初步结果表明西酞普兰是一种有效且耐受性良好的抗抑郁药。
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