Butureanu Tudor, Balan Raluca Anca, Socolov Razvan, Ioanid Nicolae, Socolov Demetra, Gafitanu Dumitru
Department of Mother and Child Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iaşi, Romania.
Department of Morphofunctional Sciences I-Histology, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iaşi, Romania.
Diagnostics (Basel). 2022 Apr 5;12(4):904. doi: 10.3390/diagnostics12040904.
Placenta accreta spectrum disorder (PAS) has an increased frequency due to the high number of cesarean sections. The abnormal placentation associated with a retained placenta can cause persistent uterine bleeding, with ultrasound Doppler examination being the main choice to assess the uterine hemorrhage. An acquired uterine arteriovenous malformation (AVM) may occur because of uterine trauma, spontaneous abortion, dilation and curettage, endometrial carcinoma or gestational trophoblastic disease. The treatment for abnormal placentation associated with AVM can be conservative, represented by methotrexate therapy, arterial embolization, uterine curettage, hysteroscopic loop resection or radical, which takes into consideration total hysterectomy. Therapeutic management always considers the degree of placental invasion, the patient hemodynamic state and fertility preservation. Considering the aspects described, we present a case of retained placenta percreta associated with acquired uterine AVM, with imagistic and clinical features suggestive of a gestational trophoblastic disease, successfully treated by hysterectomy, along with a small review of the literature, as only a few publications have reported a similar association of diagnostics and therapy.
由于剖宫产数量众多,胎盘植入谱系疾病(PAS)的发病率有所上升。与胎盘滞留相关的异常胎盘着床可导致持续性子宫出血,超声多普勒检查是评估子宫出血的主要选择。后天性子宫动静脉畸形(AVM)可能因子宫创伤、自然流产、刮宫、子宫内膜癌或妊娠滋养细胞疾病而发生。与AVM相关的异常胎盘着床的治疗可以是保守的,以甲氨蝶呤治疗、动脉栓塞、刮宫、宫腔镜环形切除术为代表,或者是根治性的,即考虑行全子宫切除术。治疗管理总是要考虑胎盘侵入的程度、患者的血流动力学状态和生育功能的保留。考虑到上述情况,我们报告一例与后天性子宫AVM相关的穿透性胎盘滞留病例,其影像学和临床特征提示为妊娠滋养细胞疾病,通过子宫切除术成功治疗,并对文献进行简要回顾,因为只有少数出版物报道了类似的诊断和治疗关联。