Lin Jui-Yen, Kang Eugene Yu-Chuan, Banker Alay S, Chen Kuan-Jen, Hwang Yih-Shiou, Lai Chi-Chun, Huang Jhen-Ling, Wu Wei-Chi
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan 333, Taiwan.
College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Diagnostics (Basel). 2022 Apr 10;12(4):945. doi: 10.3390/diagnostics12040945.
This study aimed to compare the clinical performance between a smartphone-based fundus photography device and a contact imaging device for retinopathy of prematurity (ROP) screening. All patients were first examined with binocular indirect ophthalmoscopy (BIO), which served as the reference standard. The patients were then assessed by two devices. Imaging quality, ability to judge the zone and stage of ROP, agreement with the BIO results, vital signs, and pain scores were compared between these two devices. In total, 142 eyes of 71 infants were included. For the smartphone-based fundus photography, image quality was graded excellent or acceptable in 91.4% of examinations, although it was still significantly inferior to that of the contact imaging device (p < 0.001). The smartphone-based fundus photography images had moderate agreement with the BIO results regarding the presence or absence of plus disease (Cohen’s κ = 0.619), but evaluating the zone (p < 0.001) and stage (p < 0.001) of ROP was difficult. Systemic parameters, except for heart rate, were similar between the two imaging devices (all p > 0.05). In conclusion, although the smartphone-based fundus photography showed moderate agreement for determining the presence or absence of plus disease, it failed to identify the zone and stage of ROP.
本研究旨在比较基于智能手机的眼底摄影设备与接触式成像设备在早产儿视网膜病变（ROP）筛查中的临床性能。所有患者首先接受双目间接检眼镜检查（BIO），该检查作为参考标准。然后用这两种设备对患者进行评估。比较这两种设备的成像质量、判断ROP区域和阶段的能力、与BIO结果的一致性、生命体征和疼痛评分。总共纳入了71名婴儿的142只眼睛。对于基于智能手机的眼底摄影，在91.4%的检查中图像质量被评为优秀或可接受，尽管其仍显著低于接触式成像设备（p<0.001）。基于智能手机的眼底摄影图像在有无附加病变方面与BIO结果有中度一致性（Cohen's κ=0.619），但评估ROP的区域（p<0.001）和阶段（p<0.001）较为困难。两种成像设备之间除心率外的全身参数相似（所有p>0.05）。总之，尽管基于智能手机的眼底摄影在确定有无附加病变方面显示出中度一致性，但它无法识别ROP的区域和阶段。
