• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

尸胺是节杆菌素和铁载体E生物合成过程中的一种中间体(作者译)

[Cadaverine is an intermediate in the biosynthesis of arthrobactin and ferrioxamine E (author's transl)].

作者信息

Schafft M, Diekmann H

出版信息

Arch Microbiol. 1978 May 30;117(2):203-7. doi: 10.1007/BF00402309.

DOI:10.1007/BF00402309
PMID:354550
Abstract

Cadaverin was more readily incorporated than lysine into arthrobactin from Arthrobacter pascens and into ferrioxamin E from Streptomyces glaucescens. From a racemic mixture only the L-isomer of lysine is incorporated. The L-lysine decarboxylase activity was measured in vivo and in vitro. The enzyme from Arthrobacter pascens is not inducable by lysine and completely repressed by 5.10(-6) M Fe3+. In Klebsiella pneumoniae, the producer of aerobactin, only a very low activity of L-lysine decarboxylase was detected.

摘要

尸胺比赖氨酸更容易掺入来自巴斯德节杆菌的节杆菌素以及来自青色链霉菌的铁载体E中。从外消旋混合物中,只有赖氨酸的L-异构体被掺入。在体内和体外测量了L-赖氨酸脱羧酶活性。来自巴斯德节杆菌的酶不能被赖氨酸诱导,并且被5×10⁻⁶ M Fe³⁺完全抑制。在需氧菌素的产生菌肺炎克雷伯菌中,仅检测到非常低的L-赖氨酸脱羧酶活性。

相似文献

1
[Cadaverine is an intermediate in the biosynthesis of arthrobactin and ferrioxamine E (author's transl)].尸胺是节杆菌素和铁载体E生物合成过程中的一种中间体(作者译)
Arch Microbiol. 1978 May 30;117(2):203-7. doi: 10.1007/BF00402309.
2
Functional Study of Lysine Decarboxylases from Klebsiella pneumoniae in Escherichia coli and Application of Whole Cell Bioconversion for Cadaverine Production.肺炎克雷伯菌赖氨酸脱羧酶在大肠杆菌中的功能研究及全细胞生物转化法生产尸胺的应用
J Microbiol Biotechnol. 2016 Sep 28;26(9):1586-92. doi: 10.4014/jmb.1602.02030.
3
Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.链霉菌属中赖氨酸的分解代谢主要通过尸胺进行:β-内酰胺类抗生素产生菌也会生成α-氨基己二酸。
J Bacteriol. 1989 Jan;171(1):299-302. doi: 10.1128/jb.171.1.299-302.1989.
4
Simultaneously Enhancing the Stability and Catalytic Activity of Multimeric Lysine Decarboxylase CadA by Engineering Interface Regions for Enzymatic Production of Cadaverine at High Concentration of Lysine.通过工程化界面区域提高赖氨酸脱羧酶 CadA 的稳定性和催化活性以实现高浓度赖氨酸条件下腐胺的酶法生产
Biotechnol J. 2017 Nov;12(11). doi: 10.1002/biot.201700278. Epub 2017 Sep 14.
5
Changes in cadaverine and putrescine metabolism in the mouse kidney induced to growth by an anabolic steroid.合成代谢类固醇诱导生长的小鼠肾脏中尸胺和腐胺代谢的变化。
Acta Physiol Scand. 1982 Feb;114(2):225-33. doi: 10.1111/j.1748-1716.1982.tb06976.x.
6
New enzymatic methods for selective assay of L-lysine using an L-lysine specific decarboxylase/oxidase from Burkholderia sp. AIU 395.
J Biosci Bioeng. 2015 Mar;119(3):369-74. doi: 10.1016/j.jbiosc.2014.08.013. Epub 2014 Oct 2.
7
Cadaverine Production by Using Cross-Linked Enzyme Aggregate of Lysine Decarboxylase.利用赖氨酸脱羧酶交联酶聚集体生产尸胺
J Microbiol Biotechnol. 2017 Feb 28;27(2):289-296. doi: 10.4014/jmb.1608.08033.
8
Siderophore production of Klebsiella species isolated from different sources.从不同来源分离的克雷伯菌属细菌的铁载体产生情况。
Zentralbl Bakteriol. 1992 Apr;276(4):481-6. doi: 10.1016/s0934-8840(11)80673-0.
9
Optimization of Direct Lysine Decarboxylase Biotransformation for Cadaverine Production with Whole-Cell Biocatalysts at High Lysine Concentration.在高赖氨酸浓度下使用全细胞生物催化剂优化直接赖氨酸脱羧酶生物转化生产尸胺的工艺。
J Microbiol Biotechnol. 2015 Jul;25(7):1108-13. doi: 10.4014/jmb.1412.12052.
10
Metabolic diversification of nitrogen-containing metabolites by the expression of a heterologous lysine decarboxylase gene in Arabidopsis.通过在拟南芥中表达异源赖氨酸脱羧酶基因实现含氮代谢物的代谢多样化。
Plant J. 2019 Nov;100(3):505-521. doi: 10.1111/tpj.14454. Epub 2019 Aug 27.

引用本文的文献

1
Iron Chelation in Soil: Scalable Biotechnology for Accelerating Carbon Dioxide Removal by Enhanced Rock Weathering.土壤中铁螯合作用:通过增强岩石风化促进二氧化碳去除的可扩展生物技术。
Environ Sci Technol. 2024 Jul 9;58(27):11970-11987. doi: 10.1021/acs.est.3c10146. Epub 2024 Jun 24.
2
Multiple siderophores: bug or feature?多种铁载体:是缺陷还是特征?
J Biol Inorg Chem. 2018 Oct;23(7):983-993. doi: 10.1007/s00775-018-1617-x. Epub 2018 Sep 27.
3
Characterization of an iron-regulated promoter involved in desferrioxamine B synthesis in Streptomyces pilosus: repressor-binding site and homology to the diphtheria toxin gene promoter.

本文引用的文献

1
[Metabolic products of microorganisms. 106. The structure of Terregens factor].[微生物的代谢产物。106. 土栖菌素因子的结构]
Arch Mikrobiol. 1972;85(1):44-50.
2
Antibiotics and other naturally occurring hydroxamic acids and hydroxamates.
Pure Appl Chem. 1971;28(4):603-36. doi: 10.1351/pac197128040603.
3
Regulation of synthesis of 2,3-dihydroxybenzoic acid in Bacillus subtilis by iron and a biological secondary hydroxamate.铁和一种生物次生异羟肟酸对枯草芽孢杆菌中2,3-二羟基苯甲酸合成的调控
J Bacteriol. 1993 Jun;175(11):3295-302. doi: 10.1128/jb.175.11.3295-3302.1993.
4
Proferrioxamine synthesis in Erwinia amylovora in response to precursor or hydroxylysine feeding: metabolic profiling with liquid chromatography-electrospray mass spectrometry.解淀粉欧文氏菌中响应前体或羟赖氨酸添加的去铁胺合成:液相色谱-电喷雾质谱代谢谱分析
Biometals. 1995 Oct;8(4):318-27. doi: 10.1007/BF00141605.
Biochim Biophys Acta. 1968 Oct 15;165(3):563-6. doi: 10.1016/0304-4165(68)90244-4.
4
Regulation of 2,3-dihydroxybenzoylserine synthetase by iron.铁对2,3-二羟基苯甲酰丝氨酸合成酶的调控
J Biol Chem. 1968 Feb 10;243(3):510-3.
5
Enzymatic N-acetylation of lysine analogs. Purification and properties of acetyl coenzyme A:S-(beta-aminoethyl)-L-cysteine omega-N-acetyltransferase.
J Biol Chem. 1974 Aug 25;249(16):5285-9.
6
Regulation of amino acid decarboxylation.氨基酸脱羧作用的调节
Annu Rev Biochem. 1974;43(0):303-25. doi: 10.1146/annurev.bi.43.070174.001511.
7
Structure of schizokinen, an iron-transport compound from Bacillus megaterium.巨大芽孢杆菌铁转运化合物裂殖素的结构
Biochemistry. 1971 Dec 21;10(26):4894-8. doi: 10.1021/bi00802a010.
8
The isolation and characterization of a hydroxamic acid (aerobactin) formed by Aerobacter aerogenes 62-I.产气气杆菌62-I所形成的一种异羟肟酸(气杆菌素)的分离与鉴定
Biochim Biophys Acta. 1969 Nov 18;192(2):175-84. doi: 10.1016/0304-4165(69)90353-5.
9
Regulation of the enzymes involved in the biosynthesis of 2,3-dihydroxybenzoic acid in Aerobacter aerogenes and Escherichia coli.产气气杆菌和大肠杆菌中2,3 - 二羟基苯甲酸生物合成相关酶的调控
Biochim Biophys Acta. 1969 May 6;177(3):401-11. doi: 10.1016/0304-4165(69)90302-x.