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尸胺是节杆菌素和铁载体E生物合成过程中的一种中间体(作者译)

[Cadaverine is an intermediate in the biosynthesis of arthrobactin and ferrioxamine E (author's transl)].

作者信息

Schafft M, Diekmann H

出版信息

Arch Microbiol. 1978 May 30;117(2):203-7. doi: 10.1007/BF00402309.

Abstract

Cadaverin was more readily incorporated than lysine into arthrobactin from Arthrobacter pascens and into ferrioxamin E from Streptomyces glaucescens. From a racemic mixture only the L-isomer of lysine is incorporated. The L-lysine decarboxylase activity was measured in vivo and in vitro. The enzyme from Arthrobacter pascens is not inducable by lysine and completely repressed by 5.10(-6) M Fe3+. In Klebsiella pneumoniae, the producer of aerobactin, only a very low activity of L-lysine decarboxylase was detected.

摘要

尸胺比赖氨酸更容易掺入来自巴斯德节杆菌的节杆菌素以及来自青色链霉菌的铁载体E中。从外消旋混合物中,只有赖氨酸的L-异构体被掺入。在体内和体外测量了L-赖氨酸脱羧酶活性。来自巴斯德节杆菌的酶不能被赖氨酸诱导,并且被5×10⁻⁶ M Fe³⁺完全抑制。在需氧菌素的产生菌肺炎克雷伯菌中,仅检测到非常低的L-赖氨酸脱羧酶活性。

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